What is AnaptysBio, Inc.'s net margin?

AnaptysBio, Inc. (ANAB) reported net margin of -49.9% in Q3 2025.

How has AnaptysBio, Inc.'s net margin changed year-over-year?

AnaptysBio, Inc.'s net margin increased by 82.8% year-over-year, from -289.8% to -49.9%.

What is the long-term trend for AnaptysBio, Inc.'s net margin?

Over 3 years (2021 to 2024), AnaptysBio, Inc.'s net margin has grown at a 20.3% compound annual growth rate (CAGR), from -91.5% to -159.1%.

What does net margin mean?

Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.

AnaptysBio, Inc. ANAB Net margin

Net margin at other companies

Bristol-Myers SquibbBMY

15%+3.8pp

Eli LillyLLY

35%+12.3pp

PfizerPFE

15.7%—

AmgenAMGN

21%+3.6pp

Regeneron PharmaceuticalsREGN

29.6%-2.3pp

BiogenBIIB

14.3%-0.8pp

Other financials

Income statement

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Revenue$25.6M-8.0%

Operating income-$34.6M-25.8%

Net income-$52.9M-34.5%

EPS (diluted)-$1.84-43.8%

Balance sheet

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Cash & equivalents$248.5M+152%

Total debt$13.6K-99.9%

Total equity$12.7M-62.5%

Total assets$329.7M-21.9%

Cash flow

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Operating cash flow-$25.9M-142%

CapEx$17.0K-51.4%

Free cash flow-$25.9M-142%

Valuation

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Market cap$1.73B+180%

Enterprise value$1.48B+176%

P/S7.4×+1.9×

Profitability

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Operating margin17.6%+9.6pp

FCF margin1.9%+1.0pp

Returns & leverage

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Return on equity-343.8%-1,012pp

Debt / equity0×-0.5×

Current ratio7.6×-0.7×

Where this comes from

Calculated from AnaptysBio, Inc.’s reported figures.

net income/total revenue=-49.9%

Based on trailing twelve months.

The official record: AnaptysBio, Inc.’s 10-Q, filed November 4, 2025, on SEC EDGAR. View the filing →

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Questions, answered.

What is AnaptysBio, Inc.'s net margin?: AnaptysBio, Inc. (ANAB) reported net margin of -49.9% in Q3 2025.
How has AnaptysBio, Inc.'s net margin changed year-over-year?: AnaptysBio, Inc.'s net margin increased by 82.8% year-over-year, from -289.8% to -49.9%.
What is the long-term trend for AnaptysBio, Inc.'s net margin?: Over 3 years (2021 to 2024), AnaptysBio, Inc.'s net margin has grown at a 20.3% compound annual growth rate (CAGR), from -91.5% to -159.1%.
What does net margin mean?: Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.