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Annexon ANNX Q4 2025 Annual earnings

Reported March 30, 2026 · Before market open

EPS-$0.28Beat by $0.04
Revenue estimate$3.3M
EPS estimate-$0.32

Next report

Aug 13, 2026 (In 2 weeks)
Revenue estimate$6.5M
EPS estimate-$0.23

Financials

Q4 2025

Income statement

See full
Operating income-$50.3M+4.2%
Net income-$48.3M+0.7%
EPS (diluted)-$0.26+21.2%

Balance sheet

See full
Cash & equivalents$162.1M+227%
Total debt$26.2M-9.6%
Total equity$211.6M-27.8%
Total assets$277.6M-20.7%

Cash flow

See full
Operating cash flow-$45.9M-27.5%
CapEx--100%
Free cash flow-$45.9M-27.5%

Valuation & ratios

Valuation

as of 12/31/25
See full
Market cap$748.26M+36.8%
Enterprise value$612.41M+16.4%

Returns & leverage

See full
Return on equity-81.9%+129pp
Debt / equity0.1×0.0×
Current ratio5.7×-4.7×

Versus estimates

Diluted EPS

Q1 2026-$0.23Beat by $0.07
Q4 2025-$0.28Beat by $0.04
Q3 2025-$0.37Miss by $0.03Q2 2025-$0.34Beat by $0.02Q1 2025-$0.37Miss by $0.07Q4 2024-$0.33Miss by $0.05

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Questions, answered.

When did Annexon report Q4 2025 earnings?
Annexon (ANNX) reported Q4 2025 earnings on March 30, 2026 before market open.
What were Annexon's Q4 2025 revenue and EPS?
Annexon reported eps of $-0.28 for Q4 2025.
Did Annexon beat estimates in Q4 2025?
EPS beat the consensus estimate of $-0.32 by $0.04.
How did Annexon's Q4 2025 results compare year-over-year?
Compared to the same quarter a year prior, eps grew 15.2% from $-0.33.
Where can I find Annexon's Q4 2025 SEC filings?
You can read the 8-K earnings release (0001193125-26-131746) and the 10-K periodic report (0001193125-26-131782) directly on SEC EDGAR. The filing index links above go to sec.gov.