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Annexon ANNX Return on invested capital

Return on invested capital at other companies

Regeneron Pharmaceuticals logo
Regeneron PharmaceuticalsREGN
10.3%-2.0pp
Dianthus Therapeutics logo
Dianthus TherapeuticsDNTH
-35.2%-8.3pp
Vor Biopharma logo
Vor BiopharmaVOR
-153.1%-5,641pp
Cullinan Therapeutics, Inc. logo
Cullinan Therapeutics, Inc.CGEM
-58%+22.6pp
Nektar Therapeutics logo
Nektar TherapeuticsNKTR
-35.4%-12.2pp
AnaptysBio, Inc. logo
AnaptysBio, Inc.ANAB
-255.3%-510pp

Other financials

Income statement

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Operating income-$46.1M+19.8%
Net income-$44.1M+18.8%
EPS (diluted)-$0.23+37.8%

Balance sheet

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Cash & equivalents$175.2M+80.4%
Total debt$25.4M-10.2%
Total equity$204.5M-16.1%
Total assets$262.9M-13.2%

Cash flow

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Operating cash flow-$46.8M+6.5%
CapEx--100%
Free cash flow-$46.8M+6.6%

Valuation

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Market cap$843.79M+223%
Enterprise value$694.02M+261%

Returns & leverage

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Return on equity-87.6%+42.3pp
Debt / equity0.1×0.0×
Current ratio6.4×-1.6×

Where this comes from

Calculated from Annexon’s reported figures.

Based on trailing twelve months.

The official record: Annexon’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Annexon's return on invested capital?
Annexon (ANNX) reported return on invested capital of -178.5% in Q1 2026.
How has Annexon's return on invested capital changed year-over-year?
Annexon's return on invested capital decreased by 54.3% year-over-year, from -115.7% to -178.5%.
What is the long-term trend for Annexon's return on invested capital?
Over 3 years (2022 to 2025), Annexon's return on invested capital has grown at a 10.4% compound annual growth rate (CAGR), from -92.2% to -124.2%.
What does return on invested capital mean?
Net operating profit after tax (operating income taxed at the effective rate) divided by average invested capital (debt plus equity minus cash). Measures the after-tax return on all capital put to work in the business, independent of capital structure.