What is Alto Neuroscience's return on equity?

Alto Neuroscience (ANRO) reported return on equity of -38.9% in Q1 2026.

How has Alto Neuroscience's return on equity changed year-over-year?

Alto Neuroscience's return on equity decreased by 2.1% year-over-year, from -38% to -38.9%.

What does return on equity mean?

Trailing-twelve-month net income divided by average shareholders' equity (average of the start and end of the trailing-twelve-month window). Measures the profit generated on each dollar of shareholder capital.

Alto Neuroscience ANRO Return on equity

Return on equity at other companies

Xenon PharmaceuticalsXENE

-37.5%+8.7pp

Acadia PharmaceuticalsACAD

37.3%+0.1pp

Rapport Therapeutics, Inc.RAPP

-28.3%—

Praxis Precision Medicines, Inc.PRAX

-35.3%-10.9pp

MeiraGTx Holdings plcMGTX

-379.5%—

Axsome TherapeuticsAXSM

-349.4%+109pp

Other financials

Income statement

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Operating income-$27.1M-73.1%

Net income-$26.2M-73.0%

EPS (diluted)-$0.80-42.9%

Balance sheet

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Cash & equivalents$264.3M+63.9%

Total debt$20.9M-17.2%

Total equity$243.4M+75.0%

Total assets$276.3M+60.7%

Cash flow

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Operating cash flow-$27.1M-63.6%

CapEx$556.0K+2,217%

Free cash flow-$27.6M-66.7%

Valuation

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Market cap$874.19M+1,335%

Enterprise value$630.81M-940%

Returns & leverage

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Debt / equity0.1×-0.1×

Current ratio20.5×-2.0×

Where this comes from

Calculated from Alto Neuroscience’s reported figures.

net income/total stockholders equity=-38.9%

Based on trailing twelve months.

The official record: Alto Neuroscience’s 10-Q, filed May 13, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Alto Neuroscience's return on equity?: Alto Neuroscience (ANRO) reported return on equity of -38.9% in Q1 2026.
How has Alto Neuroscience's return on equity changed year-over-year?: Alto Neuroscience's return on equity decreased by 2.1% year-over-year, from -38% to -38.9%.
What does return on equity mean?: Trailing-twelve-month net income divided by average shareholders' equity (average of the start and end of the trailing-twelve-month window). Measures the profit generated on each dollar of shareholder capital.