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Axsome Therapeutics

AXSM

Axsome Therapeutics is a fully integrated biopharmaceutical company dedicated to developing and commercializing innovative therapies for central nervous system (CNS) disorders.

Market cap
$12.27B+146%
Revenue$708.2M+63.9%
Net income-$188.3M+32.3%
Free cash flow-$72.0M+39.4%
EPS (diluted)-$3.72+35.5%
Trailing twelve months · change vs. prior year

Earnings

Next report

Aug 10, 2026 (In 1 week)
Revenue estimate$220.9M
EPS estimate-$0.89

Financials

Q1 2026

Income statement

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Revenue$191.2M+57.4%
Gross profit$176.5M+58.0%
Operating income-$63.4M-11.2%
Net income-$64.5M-8.6%
EPS (diluted)-$1.26-3.3%

Balance sheet

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Cash & equivalents$305.1M+1.4%
Total debt$219.9M+4.1%
Total equity$54.6M+2.6%
Total assets$713.6M+19.6%

Cash flow

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Operating cash flow-$20.7M+52.3%
CapEx$121.0K-64.2%
Free cash flow-$20.8M+52.4%

Valuation & ratios

Valuation

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Market cap$12.27B+146%
Enterprise value$12.18B+151%
P/S17.3×+7.3×

Profitability

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Gross margin92.6%+1.1pp
Operating margin-24.4%-9.3pp
Net margin-26.6%-9.8pp
FCF margin-10.2%-3.9pp

Returns & leverage

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Return on equity-349.4%+109pp
Debt / equity+0.1×
Current ratio1.4×-0.6×

Segments

By product

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Royalty$4.1M+269%
Royalty And Milestone Revenue$1.8M+63.2%
Milestone Revenue$500.0K

Competitors

Profile

Axsome Therapeutics is a fully integrated biopharmaceutical company dedicated to developing and commercializing innovative therapies for central nervous system (CNS) disorders. The company leverages proprietary medicinal chemistry and formulation technologies to address significant gaps in care for psychiatric and neurological conditions. Its value proposition is centered on delivering differentiated products with novel mechanisms of action to transform patient outcomes in underserved therapeutic segments.

Competitive position

Axsome is a commercial-stage biopharmaceutical company with a growing portfolio of approved CNS drugs and a late-stage pipeline utilizing the 505(b)(2) regulatory pathway to reduce development risk.

GeographiesUnited States, Europe, Middle East, North Africa
Customer segmentsHealthcare Providers, Patients, Wholesale Distributors
Business modelResearch and Development, Direct-to-Market Pharmaceutical Sales, Licensing and Royalties
SuppliersContract Manufacturing Organizations (CMOs), Raw Material Suppliers, Clinical Research Organizations (CROs)
CustomersSpecialty Pharmacies, Wholesale Drug Distributors, Hospitals, Retail Pharmacies
Listed2015
Employees569.0
CEOHerriot Tabuteau
Websiteaxsome.com
FilingsSEC EDGAR

Questions, answered.

What is Axsome Therapeutics's market cap?
Axsome Therapeutics (AXSM) has a market capitalization of $12.3B and trades on NASDAQ.
What is Axsome Therapeutics's revenue and profitability?
Axsome Therapeutics generated $708.2M in trailing twelve-month revenue with a net loss of $188.3M, representing a net margin of -26.6%. Gross margin stands at 92.6%, with free cash flow of -$72.0M. These figures are based on the Q1 2026 filing.
Who are Axsome Therapeutics's competitors?
Axsome Therapeutics's key competitors include AbbVie Inc., Eli Lilly and Company, Harmony Biosciences LLC, and others. These companies compete in similar markets and product categories.
Who does Axsome Therapeutics partner with?
Axsome Therapeutics's notable partners include Pfizer Inc., Jazz Pharmaceuticals plc, Atnahs Pharma UK Limited (Pharmanovia), and others.
What subsidiaries does Axsome Therapeutics have?
Axsome Therapeutics's subsidiaries include Baergic Bio, Inc..
Where is Axsome Therapeutics headquartered?
Axsome Therapeutics is headquartered in United States of America and employs approximately 569 people. It has been publicly traded since 2015.