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CRISPR Therapeutics CRSP Return on invested capital

Return on invested capital at other companies

CG Oncology logo
CG OncologyCGON
-24.9%+1.8pp
Cogent Biosciences, Inc. logo
Cogent Biosciences, Inc.COGT
-147.2%-18.7pp
Arrowhead Research logo
Arrowhead ResearchARWR
-38.8%+135pp
Krystal Biotech, Inc. logo
Krystal Biotech, Inc.KRYS
24.3%+7.1pp
Incyte logo
IncyteINCY
65.6%+61.0pp
Revvity logo
RevvityRVTY
3.6%+0.5pp

Other financials

Income statement

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Revenue$1.5M+68.6%
Operating income-$130.2M+12.2%
Net income-$122.9M+9.6%
EPS (diluted)-$1.28+19.0%

Balance sheet

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Cash & equivalents$423.3M+80.0%
Total debt$787.6M+259%
Total equity$1.8B-0.8%
Total assets$2.7B+25.8%

Cash flow

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Operating cash flow-$108.9M-102%
CapEx$504.0K+145%
Free cash flow-$109.4M-102%

Valuation

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Market cap$5.33B+56.4%
Enterprise value$5.69B+69.8%
P/S1,298.3×+1,208×

Profitability

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Operating margin-15,754.2%-17,253pp
Net margin-13,856.5%-15,058pp
FCF margin-9,777.6%-10,759pp

Returns & leverage

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Return on equity-31.2%+43.7pp
Debt / equity0.4×+0.3×
Current ratio18×+2.3×

Where this comes from

Calculated from CRISPR Therapeutics’s reported figures.

Based on trailing twelve months.

The official record: CRISPR Therapeutics’s 10-Q, filed May 4, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is CRISPR Therapeutics's return on invested capital?
CRISPR Therapeutics (CRSP) reported return on invested capital of -32.4% in Q1 2026.
How has CRISPR Therapeutics's return on invested capital changed year-over-year?
CRISPR Therapeutics's return on invested capital decreased by 16.9% year-over-year, from -27.7% to -32.4%.
What is the long-term trend for CRISPR Therapeutics's return on invested capital?
Over 3 years (2020 to 2025), CRISPR Therapeutics's return on invested capital has grown at a -32.2% compound annual growth rate (CAGR), from -117.1% to -36.5%.
What does return on invested capital mean?
Net operating profit after tax (operating income taxed at the effective rate) divided by average invested capital (debt plus equity minus cash). Measures the after-tax return on all capital put to work in the business, independent of capital structure.