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CytomX Therapeutics

CTMX

CytomX Therapeutics is a clinical-stage biopharmaceutical company specializing in the development of conditionally activated biologics for oncology.

Market cap
$707.53M+93.6%
Revenue$35.5M-75.9%
Net income-$59.1M-242%
Free cash flow-$80.2M+1.7%
EPS (diluted)-$0.41-184%
Trailing twelve months · change vs. prior year

Earnings

Next report

Aug 6, 2026 (In 1 week)
Revenue estimate$12.4M
EPS estimate-$0.11

Financials

Q1 2026

Income statement

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Revenue$10.3M-79.9%
Operating income-$19.7M-187%
Net income-$18.2M-178%
EPS (diluted)-$0.10-137%

Balance sheet

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Cash & equivalents$28.8M-39.4%
Total debt$2.9M-65.0%
Total equity$319.9M+1,177%
Total assets$359.4M+265%

Cash flow

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Operating cash flow-$25.5M-21.4%
CapEx--100%
Free cash flow-$25.5M-20.7%

Valuation & ratios

Valuation

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Market cap$707.53M+93.6%
Enterprise value$681.56M+104%
P/S19.9×+17.2×

Profitability

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Operating margin-181.9%-206pp
Net margin-166.4%-195pp
FCF margin-225.6%-334pp

Returns & leverage

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Return on equity-34.3%
Debt / equity-0.3×
Current ratio10.4×+8.7×

Competitors

Profile

CytomX Therapeutics is a clinical-stage biopharmaceutical company specializing in the development of conditionally activated biologics for oncology. The company utilizes its proprietary PROBODY technology platform to design masked antibodies that are activated by proteases specifically within the tumor microenvironment. This approach aims to minimize systemic toxicity and expand the therapeutic index for potent drug modalities such as antibody-drug conjugates and T-cell engagers.

Competitive position

A pioneer in the field of conditionally activated biologics with over 15 years of experience in protease-inhibited masking technology.

GeographiesGlobal, United States
Customer segmentsBiopharmaceutical partners, Healthcare providers
Business modelR&D, Licensing, Biopharmaceutical development
SuppliersSpecialized payload and linker technology providers, Contract manufacturing organizations, Protease biology research
CustomersLarge pharmaceutical partners, Oncology patients, Clinical trial sites
Listed2015
Employees122.0
CEOSean A. McCarthy
Websitecytomx.com
FilingsSEC EDGAR

Questions, answered.

What is CytomX Therapeutics's market cap?
CytomX Therapeutics (CTMX) has a market capitalization of $707.5M and trades on NASDAQ.
What is CytomX Therapeutics's revenue and profitability?
CytomX Therapeutics generated $35.5M in trailing twelve-month revenue with a net loss of $59.1M, representing a net margin of -166.4%, with free cash flow of -$80.2M. These figures are based on the Q1 2026 filing.
Who are CytomX Therapeutics's competitors?
CytomX Therapeutics's key competitors include Seagen, Amgen, Immunome, Inc., and others. These companies compete in similar markets and product categories.
Who does CytomX Therapeutics partner with?
CytomX Therapeutics's notable partners include AbbVie, Bristol-Myers Squibb, Amgen.
Where is CytomX Therapeutics headquartered?
CytomX Therapeutics is headquartered in United States of America and employs approximately 122 people. It has been publicly traded since 2015.