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Exelixis EXEL Operating margin

Operating margin at other companies

Summit Therapeutics logo
Summit TherapeuticsSMMT
-268,266.8%-272,316pp
Incyte logo
IncyteINCY
30%+26.1pp
Ionis Pharmaceuticals logo
Ionis PharmaceuticalsIONS
-33.3%-11.0pp
BridgeBio Pharma logo
BridgeBio PharmaBBIO
-90.5%-41.2pp
Neurocrine Biosciences logo
Neurocrine BiosciencesNBIX
25.4%+4.9pp
ALN
Alnylam PharmaceuticalsALNY
17.5%+14.4pp

Other financials

Income statement

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Revenue$610.8M+10.0%
Gross profit$590.9M+10.2%
Operating income$251.3M+34.5%
Net income$210.5M+31.9%
EPS (diluted)$0.79+43.6%

Balance sheet

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Cash & equivalents$226.2M+23.1%
Total debt$169.5M-9.4%
Total equity$1.9B-9.2%
Total assets$2.6B-8.6%

Cash flow

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Operating cash flow$251.8M+19.1%
CapEx$1.5M-48.9%
Free cash flow$250.3M+20.1%

Valuation

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Market cap$13.05B+10.1%
Enterprise value$12.99B+9.5%
P/E15.7×-2.8×
P/S5.5×+0.3×

Profitability

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Gross margin96.4%-0.3pp
Net margin35.1%+7.1pp
FCF margin38.6%+2.9pp

Returns & leverage

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Return on equity41%+10.8pp
Debt / equity0.1×0.0×
Current ratio3.3×-0.2×

Where this comes from

Calculated from Exelixis’s reported figures.

Based on trailing twelve months.

The official record: Exelixis’s 10-Q, filed May 5, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Exelixis's operating margin?
Exelixis (EXEL) reported operating margin of 39.4% in Q1 2026.
How has Exelixis's operating margin changed year-over-year?
Exelixis's operating margin increased by 19.0% year-over-year, from 33.1% to 39.4%.
What is the long-term trend for Exelixis's operating margin?
Over 4 years (2020 to 2025), Exelixis's operating margin has grown at a 35.5% compound annual growth rate (CAGR), from 11.1% to 37.6%.
What does operating margin mean?
The profit left from core operations for every dollar of sales, before interest and taxes.
How do you interpret operating margin?
Expanding operating margin shows operating leverage — revenue growing faster than the cost base. Compression points to rising overhead, pricing pressure, or investment ahead of revenue.
How does operating margin compare across companies?
Strong cross-company signal within a sector. Capital-light businesses sustain higher operating margins than capital-intensive ones.