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Illumina Business Segments

Business, geographic, and product segment breakdowns

Illumina generates $4.4B in annual revenue across 3 key segments: Consumables ($3.3B), Instruments ($490.0M), and Service ($647.0M). The company-wide operating margin is 19.37%. Based on the Q1 2026 filing.

Consumables (TTM)$3.3BInstruments (TTM)$490.0MService (TTM)$647.0M
Latest FilingQ1 2026
Report Date2026-05-04
Market Cap$25.1B
P/E Ratio29.48
ROE33.82%

Products & Services

Total Revenue

SegmentQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Consumables$779M$768M$811M$816M$832M$797M
Service$166M$161M$147M$157M$169M$174M
Instruments$159M$112M$101M$111M$158M$120M

Cost of revenue

SegmentQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Service$81M$88M$71M$68M$72M$80M

Geographic

Total Revenue

SegmentQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
United States and Canada—$555M———$590M
Europe, Middle East, Africa and Latin America—$332M———$356M
Asia-Pacific—$82M———$93M
Greater China$80M$72M$63M$52M$56M$52M

Total long-lived assets, net

SegmentQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Singapore$279M———$281M—
United Kingdom$124M———$119M—
United States$750M———$660M—

Concentration percent

SegmentQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Outside the United States13.3%13.3%13.3%13.3%13.3%—

Revenue

SegmentQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
United States$572M$560.8M$560.8M$560.8M$560.8M—

Business Segments

Consolidated capital expenditures

SegmentQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Core Illumina$34.3M$37M$37M$37M$37M—

Cost of revenue

SegmentQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Core Illumina$376M$358M$364M$351M$400M$370M

G&A

SegmentQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Core Illumina$121M$102M$88M$129M$149M$114M

Net Income

SegmentQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Core Illumina$175M$164M$214M$227M$201M$209M

Other (expense) income, net

SegmentQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Core Illumina—$18M———-$52M

Provision for income taxes

SegmentQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Core Illumina—$51M———$23M

R&D

SegmentQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Core Illumina$256M$252M$247M$229M$239M$240M

Sales & Marketing

SegmentQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Core Illumina$158M$165M$146M$148M$160M$158M

Total Revenue

SegmentQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Sequencing$1B$947M$972M$1B$1.1B$995M
Microarray$100M$94M$87M$83M$93M$96M