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Karyopharm Therapeutics KPTI Q4 2025 Annual earnings

Reported February 12, 2026 · Before market open

Revenue$34.1MMiss by $1.0M
EPS-$3.60Miss by $1.34
Revenue estimate$35.1M
EPS estimate-$2.26

Next report

Aug 10, 2026 (In 1 week)
Revenue estimate$33.6M
EPS estimate-$1.31

Versus estimates

Revenue

Q1 2026$35.1MBeat by $3.7M
Q4 2025$34.1MMiss by $1.0M
Q3 2025$44.0MBeat by $2.0MQ2 2025$37.9MMiss by $1.6MQ1 2025$30.0MMiss by $5.1MQ4 2024$30.5MMiss by $7.3M

Diluted EPS

Q1 2026-$1.24Beat by $0.21
Q4 2025-$3.60Miss by $1.34
Q3 2025-$3.82Miss by $0.35Q2 2025-$4.32Miss by $0.52Q1 2025-$2.77Beat by $1.44Q4 2024-$3.60Beat by $0.30

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Questions, answered.

When did Karyopharm Therapeutics report Q4 2025 earnings?
Karyopharm Therapeutics (KPTI) reported Q4 2025 earnings on February 12, 2026 before market open.
What were Karyopharm Therapeutics's Q4 2025 revenue and EPS?
Karyopharm Therapeutics reported revenue of $34.1M and eps of $-3.60 for Q4 2025.
Did Karyopharm Therapeutics beat estimates in Q4 2025?
Revenue missed the consensus estimate of $35.1M by $1.0M. EPS missed the consensus estimate of $-2.26 by $1.34.
How did Karyopharm Therapeutics's Q4 2025 results compare year-over-year?
Compared to the same quarter a year prior, revenue grew 11.6% from $30.5M a year earlier and eps grew 0.0% from $-3.60.
Where can I find Karyopharm Therapeutics's Q4 2025 SEC filings?
You can read the 8-K earnings release (0001193125-26-047670) and the 10-K periodic report (0001193125-26-049397) directly on SEC EDGAR. The filing index links above go to sec.gov.