What are Lexicon Pharmaceuticals's profit margins?

Lexicon Pharmaceuticals (LXRX) runs a 99.5% gross margin and a -34.8% operating margin, with a -37.5% net margin.

Where do Lexicon Pharmaceuticals's ratios come from?

Every ratio is computed from Lexicon Pharmaceuticals's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Lexicon Pharmaceuticals LXRX Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	Q1 '26	Q4 '25	Q3 '25	Q2 '25	Q1 '25
Profitability
Gross margin	99.5%+1.5pp	99.4%+1.4pp	99.4%+5.9pp	99.2%+6.7pp	98%+3.0pp
Operating margin	-34.8%+534pp	-98.2%+536pp	-94.4%+3,943pp	-202.6%+5,210pp	-568.6%+7,477pp
Net margin	-37.5%+531pp	-101.1%+544pp	-96.8%+4,042pp	-206.4%+5,344pp	-568%+7,809pp
Returns
Return on equity	-16%+70.1pp	-39.7%+128pp	-45.9%+90.2pp	-65.3%+29.5pp	-86.1%+16.6pp
Return on invested capital	-13.5%+62.9pp	-33.5%+75.4pp	-37.5%+51.5pp	-52.5%+26.3pp	-76.3%+13.0pp
Efficiency
Asset turnover	0.2×+0.2×	0.2×+0.1×	0.3×+0.3×	0.2×+0.2×	0.1×+0.1×
Liquidity
Current ratio	18.8×+16.6×	4.9×-0.6×	5.6×-1.8×	4.2×-7.3×	2.2×-13.4×
Leverage
Debt-to-equity	0.3×-0.6×	0.6×-0.1×	0.5×-0.1×	0.5×0.0×	0.9×+0.5×
Per Share
Book value per share	$0.51+49.1%	$0.30-35.0%	$0.33-33.0%	$0.36-53.9%	$0.34-71.1%
Valuation
Market capitalization	$986.12M+262%	$417.91M+56.5%	$490.59M-13.6%	$279.76M-53.9%	$166.58M-71.8%
Price / sales	14.2×+5.4×	8.4×-0.2×	6.9×-102×	4.8×-162×	5.3×-250×
Price / book	4.9×+2.6×	3.9×+2.1×	4.1×+0.9×	2.2×-0.4×	1.4×-0.7×

Chart any of these lines over time, or line them up against competitors.

Compare these in charts →

Ask your AI about Lexicon Pharmaceuticals.

Connect your AI assistant and get a quick read on the numbers, right in your chat.

Connect your AI

Claude

Questions, answered.

What are Lexicon Pharmaceuticals's profit margins?: Lexicon Pharmaceuticals (LXRX) runs a 99.5% gross margin and a -34.8% operating margin, with a -37.5% net margin.
Where do Lexicon Pharmaceuticals's ratios come from?: Every ratio is computed from Lexicon Pharmaceuticals's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.