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Q1 '26Q4 '25Q3 '25Q2 '25Q1 '25
Profitability
Operating margin-27.7%+106pp-31.3%+245pp-41.5%+672pp-60.1%+3,563pp-134%
Net margin-27.3%+96.1pp-30.1%+229pp-39%+636pp-54.7%+3,432pp-123.4%
Returns
Return on equity-49.3%+0.8pp-42.5%+37.9pp-41.2%+88.5pp-36.3%+70.0pp-50.2%+38.6pp
Return on invested capital-46.7%+37.3pp-39.6%+44.0pp-44.8%+99.4pp-54.9%+115pp-84%+102pp
Efficiency
Asset turnover+0.7×0.8×+0.6×0.6×+0.5×0.5×+0.5×0.3×
Liquidity
Current ratio3.5×-2.4×-2.1×3.4×-2.5×5.1×-3.6×5.9×-3.5×
Leverage
Debt-to-equity0.7×+0.5×0.6×+0.4×0.6×+0.4×0.2×0.0×0.2×0.0×
Per Share
Book value per share$18.72-26.0%$21.21-24.3%$21.95-38.6%$24.65-38.4%$25.30-40.5%
Valuation
Market capitalization$12.01B+64.2%$13.23B+96.5%$10.22B+122%$6.33B+6.0%$7.31B+32.8%
Price / sales10.6×-12.4×13.8×-23.6×13.8×-46.2×12.3×-396×23×
Price / book22.1×+11.8×21.9×+13.0×16.3×+10.4×9.1×+2.1×10.3×+3.8×

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Questions, answered.

What are Madrigal Pharmaceuticals, Inc.'s profit margins?
Madrigal Pharmaceuticals, Inc. (MDGL) runs a 96.5% gross margin and a -27.7% operating margin, with a -27.3% net margin.
Where do Madrigal Pharmaceuticals, Inc.'s ratios come from?
Every ratio is computed from Madrigal Pharmaceuticals, Inc.'s SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.