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OnKure Therapeutics, Inc.

OKUR

OnKure Therapeutics is a clinical-stage biopharmaceutical company specializing in the discovery and development of precision medicines for cancers and vascular overgrowth syndromes.

Market cap
$163.6M+68.7%
Net income-$58.7M+0.5%
Free cash flow-$50.8M+6.9%
EPS (diluted)-$4.33+96.2%
Trailing twelve months · change vs. prior year

Earnings

Next report

Aug 11, 2026 (In 1 week)
Revenue estimate$166.7K
EPS estimate-$0.58

Financials

Q1 2026

Income statement

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Operating income-$15.6M+8.1%
Net income-$15.2M+4.8%
EPS (diluted)-$1.11+6.7%

Balance sheet

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Cash & equivalents$192.1M+98.7%
Total debt$409.0K-57.2%
Total equity$184.4M+103%
Total assets$198.7M+98.9%

Cash flow

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Operating cash flow-$12.9M+7.6%
CapEx$5.0K-72.2%
Free cash flow-$12.9M+7.7%

Valuation & ratios

Valuation

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Market cap$163.6M+68.7%
Enterprise value-$28.1M-295%

Returns & leverage

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Return on equity-42.7%
Debt / equity0.0×
Current ratio13.8×+2.6×

Competitors

Profile

OnKure Therapeutics is a clinical-stage biopharmaceutical company specializing in the discovery and development of precision medicines for cancers and vascular overgrowth syndromes. The company utilizes a structure-based drug design platform to create small molecule inhibitors that selectively target specific genetic mutations while sparing wild-type enzymes. This approach aims to maximize therapeutic efficacy and minimize off-target toxicities associated with non-selective inhibition.

Competitive position

OnKure is a clinical-stage developer of next-generation PI3Kα inhibitors, positioning itself as a more selective and less toxic alternative to first-generation therapies.

GeographiesUnited States
Customer segmentsAdvanced breast cancer patients, Solid tumor patients, Vascular malformation patients
Business modelR&D-based biopharmaceutical, Drug discovery and development
SuppliersX-ray crystallography services, Computational chemistry software, Contract manufacturing organizations (CMOs), Clinical research organizations (CROs)
CustomersPharmaceutical distributors, Specialty pharmacies, Healthcare providers
Listed2024
CEONicholas A. Saccomano
FilingsSEC EDGAR

Questions, answered.

What is OnKure Therapeutics, Inc.'s market cap?
OnKure Therapeutics, Inc. (OKUR) has a market capitalization of $163.6M and trades on XNAS.
Who are OnKure Therapeutics, Inc.'s competitors?
OnKure Therapeutics, Inc.'s key competitors include Pfizer, Prelude Therapeutics Incorporated, Eikon Therapeutics, Inc. Common Stock, and others. These companies compete in similar markets and product categories.
Where is OnKure Therapeutics, Inc. headquartered?
OnKure Therapeutics, Inc. is headquartered in United States of America. It has been publicly traded since 2024.