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Opko Health OPK Q4 2025 Annual earnings

Reported February 26, 2026 · After market close

Revenue$148.5MBeat by $8.7M
EPS-$0.04Beat by $0.03
Revenue estimate$139.8M
EPS estimate-$0.07

Next report

Date not yet announced

Financials

Q4 2025

Income statement

See full
Revenue$148.5M-19.2%
Gross profit$64.0M-24.4%
Operating income-$38.3M-15.6%
Net income-$31.3M-323%
EPS (diluted)-$0.04-500%

Balance sheet

See full
Total debt$396.8M+478%
Total equity$1.3B-7.1%
Total assets$1.9B-12.2%

Cash flow

See full
Operating cash flow-$25.9M+41.6%
CapEx$2.7M-50.7%
Free cash flow-$28.6M+42.6%

Valuation & ratios

Valuation

as of 12/31/25
See full
Market cap$967.3M-2.2%
Enterprise value$1.36B+29.0%
P/S1.6×+0.2×

Profitability

See full
Gross margin33.9%+3.3pp
Operating margin-19.3%-5.6pp
Net margin-37.2%-49.7pp
FCF margin-31.4%+2.6pp

Returns & leverage

See full
Return on equity-17.1%-24.2pp
Debt / equity0.3×+0.3×
Current ratio4×+0.5×

Segments

By product

See full
Transfer Of Intellectual Property And Other$33.7M-21.8%
Rayaldee$16.9M-15.0%

Versus estimates

Revenue

Q2 2026$163.5MBeat by $32.3MQ1 2026$124.2MMiss by $6.3M
Q4 2025$148.5MBeat by $8.7M
Q3 2025$151.7MBeat by $11.9MQ2 2025$156.8MMiss by $8.9MQ1 2025$150.0MMiss by $15.7M

Diluted EPS

Q2 2026-$0.01Beat by $0.07Q1 2026-$0.07In line
Q4 2025-$0.04Beat by $0.03
Q3 2025$0.03Beat by $0.05Q2 2025-$0.19Miss by $0.07Q1 2025-$0.10Miss by $0.04

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Questions, answered.

When did Opko Health report Q4 2025 earnings?
Opko Health (OPK) reported Q4 2025 earnings on February 26, 2026 after market close.
What were Opko Health's Q4 2025 revenue and EPS?
Opko Health reported revenue of $148.5M and eps of $-0.04 for Q4 2025.
Did Opko Health beat estimates in Q4 2025?
Revenue beat the consensus estimate of $139.8M by $8.7M. EPS beat the consensus estimate of $-0.07 by $0.03.
How did Opko Health's Q4 2025 results compare year-over-year?
Compared to the same quarter a year prior, revenue declined 19.1% from $183.6M a year earlier.
Where can I find Opko Health's Q4 2025 SEC filings?
You can read the 8-K earnings release (0001193125-26-076575) and the 10-K periodic report (0001193125-26-076596) directly on SEC EDGAR. The filing index links above go to sec.gov.