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Discontinued — last reported Q4 '25

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Other financials

Income statement

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Revenue$60.1M+83.8%
Gross profit$53.0M+82.3%
Operating income-$52.4M-11.4%
Net income-$55.6M-12.4%
EPS (diluted)-$0.83-2.5%

Balance sheet

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Cash & equivalents$62.1M-41.4%
Total debt$112.3M-1.1%
Total equity$122.9M+549%
Total assets$442.3M+14.4%

Cash flow

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Operating cash flow-$44.2M-9.5%
Free cash flow-$29.2M-2.4%

Valuation

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Market cap$7.62B+27.5%
Enterprise value$7.67B+28.8%
P/S35.1×-3.2×

Profitability

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Gross margin89.4%-0.2pp
Operating margin-90.9%-19.8pp
Net margin-93.3%-18.2pp
FCF margin-61.5%-14.1pp

Returns & leverage

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Return on equity-285.8%-68.9pp
Debt / equity0.9×-5.1×
Current ratio4.2×+0.9×

Where this comes from

Reported directly by Rhythm Pharmaceuticals, Inc. in its filing.

Tagged under the XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment.

The source filing: Rhythm Pharmaceuticals, Inc.’s 10-K, filed February 26, 2026.

Filed
Feb 26, 2026, 5:02 PM EST
Fiscal year
FY2025
Accession
0001628280-26-012399
Line itemYear ended December 31, 2025Year ended December 31, 2024Year ended December 31, 2023
Purchases of short-term investments(348,669)(268,313)(354,918)
Maturities of short-term investments252,469260,640354,967
Acquisition of IPR&D assets(40,000)(40,500)(5,667)
Purchases of property and equipment(953)(47)
Net cash used in investing activities(137,153)(48,173)(5,665)
Financing activities
Repayment of deferred royalty obligation(19,917)(12,900)(7,398)
Proceeds from issuance of common stock upon completion of public offering, net of offering costs188,657

Item 16. Form 10-K Summary

FAQ

What is Rhythm Pharmaceuticals, Inc.'s capex?
Rhythm Pharmaceuticals, Inc. (RYTM) reported capex of $238.25K in Q4 2025.
What is the long-term trend for Rhythm Pharmaceuticals, Inc.'s capex?
Over 3 years (2021 to 2025), Rhythm Pharmaceuticals, Inc.'s capex has grown at a 30.0% compound annual growth rate (CAGR), from $434K to $953K.
What does capex mean?
Cash spent on property, plant, and equipment — the primary measure of investment in productive capacity and infrastructure.

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