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Sionna Therapeutics, Inc. SION Q4 2025 Annual earnings

Reported March 2, 2026 · Before market open

EPS-$0.46Beat by $0.08
EPS estimate-$0.54

Next report

Aug 10, 2026 (In 1 week)
EPS estimate-$0.64

Financials

Q4 2025

Income statement

See full
Operating income-$23.6M-30.2%
Net income-$20.4M-29.0%
EPS (diluted)-$0.45+85.8%

Balance sheet

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Cash & equivalents$59.4M+53.3%
Total debt$8.7M-11.0%
Total equity$306.8M+287%
Total assets$326.0M+75.5%

Cash flow

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Operating cash flow-$16.6M-41.1%
CapEx$204.0K+656%
Free cash flow-$16.8M-42.5%

Valuation & ratios

Valuation

as of 12/31/25
See full
Market cap$1.84B—
Enterprise value$1.79B—

Returns & leverage

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Debt / equity0×—
Current ratio20.6×+6.1×

Versus estimates

Diluted EPS

Q1 2026-$0.60Miss by $0.08
Q4 2025-$0.46Beat by $0.08
Q3 2025-$0.46Beat by $0.06Q2 2025-$0.41Beat by $0.27Q1 2025-$0.62Miss by $0.17Q4 2024-$3.38Miss by $2.81

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Questions, answered.

When did Sionna Therapeutics, Inc. report Q4 2025 earnings?
Sionna Therapeutics, Inc. (SION) reported Q4 2025 earnings on March 2, 2026 before market open.
What were Sionna Therapeutics, Inc.'s Q4 2025 revenue and EPS?
Sionna Therapeutics, Inc. reported eps of $-0.46 for Q4 2025.
Did Sionna Therapeutics, Inc. beat estimates in Q4 2025?
EPS beat the consensus estimate of $-0.54 by $0.08.
How did Sionna Therapeutics, Inc.'s Q4 2025 results compare year-over-year?
Compared to the same quarter a year prior, eps grew 86.4% from $-3.38.
Where can I find Sionna Therapeutics, Inc.'s Q4 2025 SEC filings?
You can read the 8-K earnings release (0001628280-26-012993) and the 10-K periodic report (0001628280-26-012996) directly on SEC EDGAR. The filing index links above go to sec.gov.