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Syndax Pharmaceuticals

SNDX

Syndax Pharmaceuticals is a commercial-stage biopharmaceutical company focused on developing and commercializing a pipeline of first-in-class cancer therapies.

Market cap
$1.88B+119%
Revenue$217.4M+397%
Net income-$243.2M+26.6%
EPS (diluted)-$2.79+27.5%
Trailing twelve months · change vs. prior year

Earnings

Next report

Aug 3, 2026 (In 6 days)
Revenue estimate$79.4M
EPS estimate-$0.45

Financials

Q1 2026

Income statement

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Revenue$64.9M+224%
Operating income-$34.2M+59.2%
Net income-$42.7M+49.7%
EPS (diluted)-$0.48+51.0%

Balance sheet

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Cash & equivalents$130.9M-15.0%
Total debt$350.5M+4.2%
Total equity$41.6M-80.6%
Total assets$472.7M-26.2%

Cash flow

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Operating cash flow-$50.3M+47.1%

Valuation & ratios

Valuation

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Market cap$1.88B+119%
Enterprise value$2.1B+94.0%
P/S8.6×-2.3×

Profitability

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Operating margin-102.8%-47.8pp
Net margin-111.9%-51.5pp

Returns & leverage

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Return on equity-189.5%-8,509pp
Debt / equity8.4×+6.9×
Current ratio5.5×-0.3×

Competitors

Profile

Syndax Pharmaceuticals is a commercial-stage biopharmaceutical company focused on developing and commercializing a pipeline of first-in-class cancer therapies. The company leverages strategic partnerships and in-licensing to advance treatments for high-unmet-need conditions, including acute leukemias and chronic graft-versus-host disease. Its core value proposition lies in its ability to bring novel targeted inhibitors and monoclonal antibodies from clinical development to the oncology market.

Competitive position

Syndax holds a first-mover advantage with the first FDA-approved menin inhibitor and maintains a strong collaborative position through a significant co-commercialization agreement with Incyte.

GeographiesUnited States, China, Europe, Japan
Customer segmentsSpecialized Healthcare Providers, Patients
Business modelBiopharmaceutical R&D, Licensing and Royalties, Direct Sales
SuppliersContract Manufacturing Organizations (CMOs), Academic research institutions, Clinical trial cooperative groups, Raw material suppliers
CustomersSpecialty pharmacies, Hospitals, Government health programs (Medicare/Medicaid), Private health insurers
Listed2016
Employees184.0
CEOMichael A. Metzger
Websitesyndax.com
FilingsSEC EDGAR

Questions, answered.

What is Syndax Pharmaceuticals's market cap?
Syndax Pharmaceuticals (SNDX) has a market capitalization of $1.9B and trades on NASDAQ.
What is Syndax Pharmaceuticals's revenue and profitability?
Syndax Pharmaceuticals generated $217.4M in trailing twelve-month revenue with a net loss of $243.2M, representing a net margin of -111.9%. These figures are based on the Q1 2026 filing.
Who are Syndax Pharmaceuticals's competitors?
Syndax Pharmaceuticals's key competitors include Incyte, Kura Oncology, Biogen, and others. These companies compete in similar markets and product categories.
Who does Syndax Pharmaceuticals partner with?
Syndax Pharmaceuticals's notable partners include Incyte, Royalty Pharma, Eddingpharm, and others.
What subsidiaries does Syndax Pharmaceuticals have?
Syndax Pharmaceuticals's subsidiaries include Syndax Pharmaceuticals Netherlands B.V..
Where is Syndax Pharmaceuticals headquartered?
Syndax Pharmaceuticals is headquartered in United States of America and employs approximately 184 people. It has been publicly traded since 2016.