Income StatementBalance SheetCash FlowSegments
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Vertex Pharmaceuticals Cash Flow Statement

Operating, investing, and financing cash movements

Vertex Pharmaceuticals generated $4.2B in operating cash flow over the trailing twelve months. After $530.3M in capital expenditures, free cash flow was $3.7B. Free cash flow increased 2.1% year-over-year. Based on the Q1 2026 filing.

Net Cash From Operating (TTM)$4.2BNet Cash From Investing (TTM)-$1.3BNet Cash From Financing (TTM)-$2.1BCapital Expenditures (TTM)$530.3MDepreciation And Amortization Cf (TTM)$217.3MNet Change In Cash (TTM)$853.7M
Latest FilingQ1 2026
Report Date2026-05-05
Market Cap$110.28B
P/E Ratio25.42
ROE24.2%

Operating

MetricQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Other non-cash income (expense)-$16.4M-$39.2M-$57.8M$0.0-$23.1M$5.0M
Change in accounts payable$8.4M$26.2M$7.6M-$35.3M$38.3M$35.6M
Change in accounts receivable—$169.6M$18.4M$59.9M$99.4M-$39.8M
Change in inventories$147.5M$167.1M$148.6M$131.1M$77.4M$97.7M
Change in other liabilities—$22.0M-$63.2M$83.9M$105.8M$23.1M
Depreciation and amortization$46.5M$48.4M$51.7M$54.0M$55.7M$55.9M
Other Non-Cash Income (Expense)-$16.4M-$39.2M-$57.8M$0.0-$23.1M$5.0M
Other Non-cash Income (Expense)-$16.4M-$39.2M-$57.8M$0.0-$23.1M$5.0M
Other Non-cash Income (Expense)-$16.4M-$39.2M-$57.8M$0.0-$23.1M$5.0M
Net cash from operating activities-$123.2M$818.9M$1.1B$1.2B$498.0M$1.4B
Net income—$646.3M$1.0B$1.1B$1.2B$1.0B
Other non-cash income (expense)-$16.4M-$39.2M-$57.8M$0.0-$23.1M$5.0M
Goodwill and other intangible asset impairment charges$0.0$379.0M$0.0$0.0$0.0$0.0
Accrued expenses and other liabilities—$48.1M$166.6M$332.9M-$664.5M$70.5M
Increase (Decrease) in Prepaid Expense and Other Assets$164.6M$28.1M$76.4M$40.9M$250.6M-$173.4M
Other Noncash Income (Expense)-$16.4M-$39.2M-$57.8M$0.0-$23.1M$5.0M
Other Non-cash Income and Expense-$16.4M-$39.2M-$57.8M$0.0-$23.1M$5.0M
Other Non-Cash Adjustments-$16.4M-$39.2M-$57.8M$0.0-$23.1M$5.0M
Other Non-Cash Income and Expense-$16.4M-$39.2M-$57.8M$0.0-$23.1M$5.0M
Stock-based compensation$167.8M$166.1M$167.3M$194.9M$157.6M$166.4M

Investing

MetricQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Capital expenditures$92.6M$40.7M$145.7M$101.8M$149.4M$133.4M
Payment for (Proceeds from) Other Investing Activity$30.9M$5.3M$4.3M$0.0$15.9M$0.0
Proceeds From Sale And Maturity Of Available For Sale Securities$1.5B$1.6B$1.8B$1.3B$1.1B$2.2B
Net cash from investing activities-$821.9M-$55.8M-$484.5M-$117.0M-$288.1M-$431.9M
Purchases of investments$2.2B$1.6B$2.2B$1.3B$1.2B$2.5B

Financing

MetricQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Proceeds from exercises of stock options and other stock issuances$34.3M$16.7M$49.1M$7.9M$54.0M$27.0M
Other, net$900.0K-$500.0K$2.0M$1.1M$1.1M-$400.0K
Payment of Deferred Purchase Consideration$900.0K-$500.0K$2.0M$1.1M$1.1M-$400.0K
Noncontrolling interest transactions and other$900.0K-$500.0K$2.0M$1.1M$1.1M-$400.0K
Net cash from financing activities-$391.3M-$680.4M-$349.2M-$1.2B-$77.2M-$538.8M
Noncontrolling Interests Activity and Other$900.0K-$500.0K$2.0M$1.1M$1.1M-$400.0K
Repurchases of common stock$417.9M$426.1M$391.8M$1.1B$128.4M$336.9M
Taxes paid for net share settlement$7.3M$270.5M$5.9M$91.0M$2.5M$228.5M

Free Cash Flow

MetricQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Free cash flow-$197.6M$778.2M$927.4M$1.1B$348.6M$1.3B

Other

MetricQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Effect of exchange rate changes on cash-$47.3M$30.5M$57.2M$0.0$7.3M-$40.3M
Net increase (decrease) in cash-$675.9M$113.2M$296.6M$0.0$140.0M$417.1M

Supplemental

MetricQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26
Interest paid$2.7M$2.7M$3.5M$3.2M$3.0M$3.2M
Income Taxes Paid, Net$271.8M$184.4M$513.3M$479.6M$389.4M$82.3M
Net payments due to CRISPR Therapeutics AG related to finite-lived intangible assets$0.0$0.0$0.0$0.0$0.0—