What are Vertex Pharmaceuticals's profit margins?

Vertex Pharmaceuticals (VRTX) runs a 86.2% gross margin and a 38.3% operating margin, with a 35.5% net margin.

Where do Vertex Pharmaceuticals's ratios come from?

Every ratio is computed from Vertex Pharmaceuticals's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.

Vertex Pharmaceuticals VRTX Ratios & Valuation

Income Statement Balance Sheet Cash Flow Ratios Segments

Quarterly Annual TTM

YoY QoQ

Simplified Detailed

	Q1 '26	Q4 '25	Q3 '25	Q2 '25	Q1 '25
Profitability
Gross margin	86.2%+0.2pp	86.2%+0.1pp	86.3%+0.2pp	86.1%-0.3pp	86%-0.8pp
Operating margin	38.3%—	34.8%—	——	——	——
Net margin	35.5%—	32.9%—	——	——	——
Returns
Return on equity	24.2%—	22.5%—	——	——	——
Return on invested capital	26.8%+32.2pp	24.3%+24.9pp	25.7%+26.9pp	27%+28.5pp	-5.3%-35.8pp
Efficiency
Asset turnover	0.5×0.0×	0.5×0.0×	0.5×0.0×	0.5×0.0×	0.5×0.0×
Liquidity
Current ratio	3×+0.4×	2.9×+0.2×	2.4×-0.1×	2.5×0.0×	2.6×-0.9×
Leverage
Debt-to-equity	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×0.0×	0.1×+0.1×
Net debt / EBITDA	-0.7×—	-0.7×+31.5×	-0.7×—	-0.8×—	——
Per Share
Book value per share	$75.54+18.8%	$72.35+13.7%	$67.23+12.3%	$66.34+15.9%	$63.57-10.5%
Valuation
Market capitalization	$113.44B-8.9%	$115.03B+10.9%	$100.41B-16.3%	$115.63B-4.5%	$124.5B+15.3%
Price / earnings	26.1×—	29.1×—	——	——	——
Price / sales	9.3×-1.9×	9.6×+0.2×	8.6×-2.7×	10.1×-1.6×	11.2×+0.6×
Price / book	5.9×-1.7×	6.2×-0.2×	5.8×-1.9×	6.7×-1.5×	7.5×+1.7×
EV / EBITDA	22.4×—	25.5×-1,126×	22.6×—	26.5×—	——

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Questions, answered.

What are Vertex Pharmaceuticals's profit margins?: Vertex Pharmaceuticals (VRTX) runs a 86.2% gross margin and a 38.3% operating margin, with a 35.5% net margin.
Where do Vertex Pharmaceuticals's ratios come from?: Every ratio is computed from Vertex Pharmaceuticals's SEC filings — trailing-twelve-month flows over period-end balances. Valuation multiples combine those fundamentals with market data, recomputed each period. Switch between quarterly, annual, and TTM, or open any ratio for its full history and peer comparisons.