What is Alumis Inc.'s operating margin?

Alumis Inc. (ALMS) reported operating margin of -5,364% in Q1 2026.

What does operating margin mean?

Operating income as a percentage of revenue (trailing twelve months). Captures profitability from core operations after both cost of revenue and operating expenses, but before interest and taxes.

Alumis Inc. ALMS Operating margin

Operating margin at other companies

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28.4%+6.6pp

Celldex TherapeuticsCLDX

-35,688.5%-39,114pp

Dianthus TherapeuticsDNTH

-4,558.4%-9,354pp

Protagonist TherapeuticsPTGX

-192.4%-205pp

Kymera TherapeuticsKYMR

-697.7%+635pp

Spyre Therapeutics, Inc.SYRE

-39,428.9%-49,795pp

Other financials

Income statement

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Revenue$1.7M-90.0%

Operating income-$98.4M+3.1%

Net income-$93.1M+6.0%

EPS (diluted)-$0.74+59.3%

Balance sheet

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Cash & equivalents$63.9M-50.3%

Total debt$35.7M+1,881%

Total equity$567.0M+237%

Total assets$671.6M+157%

Cash flow

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Operating cash flow-$87.1M-8.4%

CapEx$164.0K+343%

Free cash flow-$87.2M-8.5%

Valuation

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Market cap$3.12B+739%

Enterprise value$3.1B+1,238%

P/S371.9×—

Profitability

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Net margin-2,825.7%—

FCF margin-4,487.4%—

Returns & leverage

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Return on equity-64.6%—

Debt / equity0.1×+0.1×

Current ratio7.5×+3.8×

Where this comes from

Calculated from Alumis Inc.’s reported figures.

operating income/total revenue=-5,364%

Based on trailing twelve months.

The official record: Alumis Inc.’s 10-Q, filed May 14, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Alumis Inc.'s operating margin?: Alumis Inc. (ALMS) reported operating margin of -5,364% in Q1 2026.
What does operating margin mean?: Operating income as a percentage of revenue (trailing twelve months). Captures profitability from core operations after both cost of revenue and operating expenses, but before interest and taxes.