What is Crinetics Pharmaceuticals's gross margin?

Crinetics Pharmaceuticals (CRNX) reported gross margin of 150% in Q1 2025.

How has Crinetics Pharmaceuticals's gross margin changed year-over-year?

Crinetics Pharmaceuticals's gross margin decreased by 9.4% year-over-year, from 165.6% to 150%.

What does gross margin mean?

Gross profit (revenue minus cost of revenue) as a percentage of revenue, on a trailing-twelve-month basis. Measures how much of each sales dollar survives the direct cost of producing the goods or services sold.

Crinetics Pharmaceuticals CRNX Gross margin

Gross margin at other companies

Neurocrine BiosciencesNBIX

98.2%-0.3pp

Corcept TherapeuticsCORT

98.3%-0.2pp

Catalyst PharmaceuticalCPRX

86%-0.2pp

Amneal Pharmaceuticals, Inc.AMRX

38.7%+2.0pp

United TherapeuticsUTHR

86.6%-2.4pp

Rhythm Pharmaceuticals, Inc.RYTM

89.4%-0.2pp

Other financials

Income statement

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Revenue$10.7M+2,873%

Gross profit$10.5M+2,818%

Operating income-$140.4M-26.0%

Net income-$127.8M-32.1%

EPS (diluted)-$1.23-18.3%

Balance sheet

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Cash & equivalents$115.1M+20.1%

Total debt$47.9M-5.8%

Total equity$1.3B+2.1%

Total assets$1.4B+2.9%

Cash flow

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Operating cash flow-$124.7M-41.0%

CapEx$820.0K-33.8%

Free cash flow-$125.5M-40.0%

Valuation

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Market cap$3.78B+21.9%

Enterprise value$3.71B+21.5%

P/S209.3×-3,875×

Profitability

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Operating margin-3,020.3%-1,463pp

Net margin-2,747.2%-1,328pp

FCF margin-2,321.7%-1,122pp

Returns & leverage

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Return on equity-39.2%+14.5pp

Debt / equity0×0.0×

Current ratio18.6×-3.9×

Where this comes from

Calculated from Crinetics Pharmaceuticals’s reported figures.

gross profit/total revenue=150%

Based on trailing twelve months.

The official record: Crinetics Pharmaceuticals’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Crinetics Pharmaceuticals's gross margin?: Crinetics Pharmaceuticals (CRNX) reported gross margin of 150% in Q1 2025.
How has Crinetics Pharmaceuticals's gross margin changed year-over-year?: Crinetics Pharmaceuticals's gross margin decreased by 9.4% year-over-year, from 165.6% to 150%.
What does gross margin mean?: Gross profit (revenue minus cost of revenue) as a percentage of revenue, on a trailing-twelve-month basis. Measures how much of each sales dollar survives the direct cost of producing the goods or services sold.