What is Amylyx Pharmaceuticals, Inc.'s gross margin?

Amylyx Pharmaceuticals, Inc. (AMLX) reported gross margin of 100% in Q2 2025.

How has Amylyx Pharmaceuticals, Inc.'s gross margin changed year-over-year?

Amylyx Pharmaceuticals, Inc.'s gross margin increased by 7.4% year-over-year, from 93.1% to 100%.

What does gross margin mean?

Gross profit (revenue minus cost of revenue) as a percentage of revenue, on a trailing-twelve-month basis. Measures how much of each sales dollar survives the direct cost of producing the goods or services sold.

Amylyx Pharmaceuticals, Inc. AMLX Gross margin

Gross margin at other companies

Crinetics PharmaceuticalsCRNX

150%-15.6pp

Agios PharmaceuticalsAGIO

90%+2.5pp

Rhythm Pharmaceuticals, Inc.RYTM

89.4%-0.2pp

uniQureQURE

90.6%-2.9pp

BioCryst PharmaceuticalsBCRX

97.8%+0.8pp

Acadia PharmaceuticalsACAD

91.5%-0.6pp

Other financials

Income statement

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Revenue-—

Gross profit-—

Operating income-$43.8M-15.8%

Net income-$41.3M-15.0%

EPS (diluted)-$0.37+11.9%

Balance sheet

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Cash & equivalents$229.1M+283%

Total debt$5.6M+307%

Total equity$273.2M+35.6%

Total assets$293.6M+33.7%

Cash flow

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Operating cash flow-$36.9M+7.4%

CapEx$86.0K+330%

Free cash flow-$28.0M+52.6%

Valuation

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Market cap$1.82B+390%

Enterprise value$1.6B+414%

Profitability

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Operating margin-47,349.8%-47,409pp

Net margin-45,096.2%-45,152pp

FCF margin-39,826.7%-39,847pp

Returns & leverage

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Return on equity-63.3%-12.2pp

Debt / equity0×0.0×

Current ratio17.9×+5.8×

Where this comes from

Calculated from Amylyx Pharmaceuticals, Inc.’s reported figures.

gross profit/total revenue=100%

Based on trailing twelve months.

The official record: Amylyx Pharmaceuticals, Inc.’s 10-Q, filed August 7, 2025, on SEC EDGAR. View the filing →

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Questions, answered.

What is Amylyx Pharmaceuticals, Inc.'s gross margin?: Amylyx Pharmaceuticals, Inc. (AMLX) reported gross margin of 100% in Q2 2025.
How has Amylyx Pharmaceuticals, Inc.'s gross margin changed year-over-year?: Amylyx Pharmaceuticals, Inc.'s gross margin increased by 7.4% year-over-year, from 93.1% to 100%.
What does gross margin mean?: Gross profit (revenue minus cost of revenue) as a percentage of revenue, on a trailing-twelve-month basis. Measures how much of each sales dollar survives the direct cost of producing the goods or services sold.