What is Amylyx Pharmaceuticals, Inc.'s net margin?

Amylyx Pharmaceuticals, Inc. (AMLX) reported net margin of -45,096.2% in Q2 2025.

How has Amylyx Pharmaceuticals, Inc.'s net margin changed year-over-year?

Amylyx Pharmaceuticals, Inc.'s net margin decreased by 81126.8% year-over-year, from -55.5% to -45,096.2%.

What does net margin mean?

Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.

Amylyx Pharmaceuticals, Inc. AMLX Net margin

Net margin at other companies

Beam TherapeuticsBEAM

-742.7%—

Crinetics PharmaceuticalsCRNX

-2,747.2%-1,328pp

Agios PharmaceuticalsAGIO

-639.8%—

Rhythm Pharmaceuticals, Inc.RYTM

-93.3%-18.2pp

Taysha Gene Therapies, Inc.TSHA

-1,738.4%+1,407pp

Sarepta Therapeutics, Inc.SRPT

4.6%+2.4pp

Other financials

Income statement

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Revenue-—

Gross profit-—

Operating income-$43.8M-15.8%

Net income-$41.3M-15.0%

EPS (diluted)-$0.37+11.9%

Balance sheet

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Cash & equivalents$229.1M+283%

Total debt$5.6M+307%

Total equity$273.2M+35.6%

Total assets$293.6M+33.7%

Cash flow

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Operating cash flow-$36.9M+7.4%

CapEx$86.0K+330%

Free cash flow-$28.0M+52.6%

Valuation

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Market cap$1.82B+390%

Enterprise value$1.6B+414%

Profitability

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Gross margin100%+6.9pp

Operating margin-47,349.8%-47,409pp

FCF margin-39,826.7%-39,847pp

Returns & leverage

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Return on equity-63.3%-12.2pp

Debt / equity0×0.0×

Current ratio17.9×+5.8×

Where this comes from

Calculated from Amylyx Pharmaceuticals, Inc.’s reported figures.

net income/total revenue=-45,096.2%

Based on trailing twelve months.

The official record: Amylyx Pharmaceuticals, Inc.’s 10-Q, filed August 7, 2025, on SEC EDGAR. View the filing →

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Questions, answered.

What is Amylyx Pharmaceuticals, Inc.'s net margin?: Amylyx Pharmaceuticals, Inc. (AMLX) reported net margin of -45,096.2% in Q2 2025.
How has Amylyx Pharmaceuticals, Inc.'s net margin changed year-over-year?: Amylyx Pharmaceuticals, Inc.'s net margin decreased by 81126.8% year-over-year, from -55.5% to -45,096.2%.
What does net margin mean?: Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.