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Castle Biosciences

CSTL

Castle Biosciences is a molecular diagnostics company that develops and commercializes innovative testing solutions for dermatologic cancers, gastroenterology, and ophthalmology.

Market cap
$724.58M+56.1%
Revenue$339.9M-2.1%
Net income-$12.8M-153%
Free cash flow$4.5M-89.2%
EPS (diluted)-$0.43-126%
Trailing twelve months · change vs. prior year

Earnings

Next report

Jul 30, 2026 (Today)
Revenue estimate$86.2M
EPS estimate-$0.44

Financials

Q1 2026

Income statement

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Revenue$83.7M-4.9%
Gross profit$63.1M-11.8%
Operating income-$18.4M+34.1%
Net income-$14.5M+43.8%
EPS (diluted)-$0.49+45.6%

Balance sheet

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Cash & equivalents$63.8M-28.9%
Total debt$36.7M+42.1%
Total equity$461.4M+4.8%
Total assets$547.8M+9.2%

Cash flow

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Operating cash flow-$22.1M-267%
CapEx$12.5M+163%
Free cash flow-$34.6M-221%

Valuation & ratios

Valuation

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Market cap$724.58M+56.1%
Enterprise value$697.54M+64.6%
P/S2.1×+0.8×

Profitability

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Gross margin77.9%-4.1pp
Operating margin-9.8%-30.8pp
Net margin-3.8%-10.2pp
FCF margin1.3%-10.7pp

Returns & leverage

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Return on equity-2.8%-10.6pp
Debt / equity0.1×0.0×
Current ratio6.7×-2.6×

Segments

By product

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Non-Dermatologic$42.6M+70.1%
Dermatologic$41.1M-34.7%

By segment

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Reportable Segment$83.7M-4.9%

Competitors

Profile

Castle Biosciences is a molecular diagnostics company that develops and commercializes innovative testing solutions for dermatologic cancers, gastroenterology, and ophthalmology. The company leverages multi-analyte assays with algorithmic analysis and machine learning to provide personalized genomic information that aids clinicians in diagnosis, risk stratification, and treatment selection.

Competitive position

A leading provider of proprietary gene expression profile tests for skin cancer with a significant established market presence in uveal melanoma and expanding footprint in gastroenterology.

GeographiesUnited States
Customer segmentsSpecialist Physicians, Medical Laboratories, Health Insurance Payors
Business modelDiagnostic Testing Services, Direct Sales, Intellectual Property Licensing
SuppliersSole-source reagent suppliers, Laboratory equipment manufacturers, Academic research institutions for IP licensing
CustomersMedicare and government payors, Commercial health insurance companies, Specialty physician clinics, Hospitals
Listed2019
Employees638.0
CEODerek J. Maetzold
FilingsSEC EDGAR

Questions, answered.

What is Castle Biosciences's market cap?
Castle Biosciences (CSTL) has a market capitalization of $724.6M and trades on NASDAQ.
What is Castle Biosciences's revenue and profitability?
Castle Biosciences generated $339.9M in trailing twelve-month revenue with a net loss of $12.8M, representing a net margin of -3.8%. Gross margin stands at 77.9%, with free cash flow of $4.5M. These figures are based on the Q1 2026 filing.
Who are Castle Biosciences's competitors?
Castle Biosciences's key competitors include Lucid Diagnostics, LabCorp, Veracyte, and others. These companies compete in similar markets and product categories.
Who does Castle Biosciences partner with?
Castle Biosciences's notable partners include SciBase Holding AB, The Washington University, ThermoFisher Scientific, Inc., and others.
What subsidiaries does Castle Biosciences have?
Castle Biosciences's subsidiaries include Previse, AltheaDx, Inc., Cernostics, Inc..
Where is Castle Biosciences headquartered?
Castle Biosciences is headquartered in United States of America and employs approximately 638 people. It has been publicly traded since 2019.