What is Castle Biosciences's net margin?

Castle Biosciences (CSTL) reported net margin of -3.8% in Q1 2026.

How has Castle Biosciences's net margin changed year-over-year?

Castle Biosciences's net margin decreased by 158.5% year-over-year, from -1.5% to -3.8%.

What is the long-term trend for Castle Biosciences's net margin?

Over 5 years (2020 to 2025), Castle Biosciences's net margin has grown at a -15.6% compound annual growth rate (CAGR), from -16.4% to -7%.

What does net margin mean?

Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.

Castle Biosciences CSTL Net margin

Net margin at other companies

Labcorp HoldingsLH

6.7%+1.1pp

VeracyteVCYT

16.2%+9.1pp

Personalis, Inc.PSNL

-148.1%+154pp

NeoGenomicsNEO

-13.3%+2.4pp

Fulgent Genetics, Inc.FLGT

-23%+43.3pp

GeneDx HoldingsWGS

-17.6%—

Other financials

Income statement

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Revenue$83.7M-4.9%

Gross profit$63.1M-11.8%

Operating income-$18.4M+34.1%

Net income-$14.5M+43.8%

EPS (diluted)-$0.49+45.6%

Balance sheet

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Cash & equivalents$63.8M-28.9%

Total debt$36.7M+42.1%

Total equity$461.4M+4.8%

Total assets$547.8M+9.2%

Cash flow

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Operating cash flow-$22.1M-267%

CapEx$12.5M+163%

Free cash flow-$34.6M-221%

Valuation

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Market cap$694.86M+29.9%

Enterprise value$667.82M+41.8%

P/S2×+0.5×

Profitability

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Gross margin77.9%-4.1pp

Operating margin-9.8%-30.8pp

FCF margin1.3%-10.7pp

Returns & leverage

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Return on equity-2.8%-10.6pp

Debt / equity0.1×0.0×

Current ratio6.7×-2.6×

Where this comes from

Calculated from Castle Biosciences’s reported figures.

net income/total revenue=-3.8%

Based on trailing twelve months.

The official record: Castle Biosciences’s 10-Q, filed May 6, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Castle Biosciences's net margin?: Castle Biosciences (CSTL) reported net margin of -3.8% in Q1 2026.
How has Castle Biosciences's net margin changed year-over-year?: Castle Biosciences's net margin decreased by 158.5% year-over-year, from -1.5% to -3.8%.
What is the long-term trend for Castle Biosciences's net margin?: Over 5 years (2020 to 2025), Castle Biosciences's net margin has grown at a -15.6% compound annual growth rate (CAGR), from -16.4% to -7%.
What does net margin mean?: Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.