What is Personalis, Inc.'s net margin?

Personalis, Inc. (PSNL) reported net margin of -148.1% in Q1 2026.

How has Personalis, Inc.'s net margin changed year-over-year?

Personalis, Inc.'s net margin decreased by 51.0% year-over-year, from -98.1% to -148.1%.

What is the long-term trend for Personalis, Inc.'s net margin?

Over 5 years (2020 to 2025), Personalis, Inc.'s net margin has grown at a 17.3% compound annual growth rate (CAGR), from -52.5% to -116.7%.

What does net margin mean?

Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.

Personalis, Inc. PSNL Net margin

Net margin at other companies

Quest DiagnosticsDGX

9.1%+0.2pp

NeoGenomicsNEO

-13.3%+2.4pp

IlluminaILMN

19.4%+12.7pp

VeracyteVCYT

16.2%+9.1pp

Guardant HealthGH

-40.1%-8.1pp

Natera, Inc.NTRA

-14.6%+0.6pp

Other financials

Income statement

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Revenue$15.5M-24.9%

Gross profit$281.0K-96.1%

Operating income-$32.2M-81.7%

Net income-$30.0M-90.7%

EPS (diluted)-$0.29-61.1%

Balance sheet

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Cash & equivalents$73.6M+3.7%

Total debt$39.0M-6.2%

Total equity$254.8M+22.9%

Total assets$325.4M+19.1%

Cash flow

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Operating cash flow-$22.5M-25.1%

CapEx$3.2M+27.1%

Free cash flow-$25.7M-25.4%

Valuation

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Market cap$1.19B+110%

Enterprise value$1.16B+115%

P/S18.4×+11.8×

Profitability

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Gross margin13.7%-19.6pp

Operating margin-158.9%-5,457pp

FCF margin-131.2%-453pp

Returns & leverage

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Return on equity-41.4%-6.7pp

Debt / equity0.2×0.0×

Current ratio6.6×-0.3×

Where this comes from

Calculated from Personalis, Inc.’s reported figures.

net income/total revenue=-148.1%

Based on trailing twelve months.

The official record: Personalis, Inc.’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Personalis, Inc.'s net margin?: Personalis, Inc. (PSNL) reported net margin of -148.1% in Q1 2026.
How has Personalis, Inc.'s net margin changed year-over-year?: Personalis, Inc.'s net margin decreased by 51.0% year-over-year, from -98.1% to -148.1%.
What is the long-term trend for Personalis, Inc.'s net margin?: Over 5 years (2020 to 2025), Personalis, Inc.'s net margin has grown at a 17.3% compound annual growth rate (CAGR), from -52.5% to -116.7%.
What does net margin mean?: Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.