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Exelixis EXEL Q4 2025 Annual earnings

Reported February 10, 2026 · After market close

Revenue$598.7MBeat by $2.1M
EPS$0.94Beat by $0.17
Revenue estimate$596.5M
EPS estimate$0.77

Next report

Nov 3, 2026 (in 2 months)
Revenue estimate$649.6M
EPS estimate$0.89

Financials

Q4 2025

Income statement

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Revenue$598.7M+5.6%
Gross profit$572.2M+4.6%
Operating income$235.2M+44.1%
Net income$244.5M+74.8%
EPS (diluted)$0.88+83.3%

Balance sheet

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Cash & equivalents$482.5M+122%
Total debt$200.9M-6.9%
Total equity$2.2B-3.7%
Total assets$2.8B-3.5%

Cash flow

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Operating cash flow$333.5M+38.8%
CapEx$1.2M-70.9%
Free cash flow$332.4M+40.7%

Valuation & ratios

Valuation

as of 01/02/26
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Market cap$11.09B+17.1%
Enterprise value$10.81B+14.2%
P/E14.2×-4.0×
P/S4.8×+0.4×

Profitability

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Gross margin96.4%-0.1pp
Operating margin37.6%+9.7pp
Net margin33.7%+9.7pp
FCF margin37.7%+6.8pp

Returns & leverage

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Return on equity35.5%+12.4pp
Debt / equity0.1×0.0×
Current ratio3.6×-0.1×

Segments

By product

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Gross product revenues$764.5M+8.6%
License revenues$66.4M+34.5%
Collaboration$52.1M+1.1%
Collaboration services revenues-$10.9M-601%
Discounts and allowances-$218.0M-15.6%

By segment

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Reportable Segment$598.7M+5.6%

FAQ

When did Exelixis report Q4 2025 earnings?
Exelixis (EXEL) reported Q4 2025 earnings on February 10, 2026 after market close.
What were Exelixis's Q4 2025 revenue and EPS?
Exelixis reported revenue of $598.7M and eps of $0.94 for Q4 2025.
Did Exelixis beat estimates in Q4 2025?
Revenue beat the consensus estimate of $596.5M by $2.1M. EPS beat the consensus estimate of $0.77 by $0.17.
How did Exelixis's Q4 2025 results compare year-over-year?
Compared to the same quarter a year prior, revenue grew 5.6% from $566.8M a year earlier and eps grew 70.9% from $0.55.
Where can I find Exelixis's Q4 2025 SEC filings?
You can read the 8-K earnings release (0000939767-26-000019) and the 10-K periodic report (0000939767-26-000021) directly on SEC EDGAR. The filing index links above go to sec.gov.