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Guardant Health GH Operating margin

Operating margin at other companies

Illumina logo
IlluminaILMN
19.4%
Natera, Inc. logo
Natera, Inc.NTRA
-13%+0.6pp
Quest Diagnostics logo
Quest DiagnosticsDGX
14.3%+0.6pp
Agilent Technologies logo
Agilent TechnologiesA
21.5%+0.1pp
Labcorp Holdings logo
Labcorp HoldingsLH
10.2%+1.9pp
Abbott logo
AbbottABT
17.1%+0.2pp

Other financials

Income statement

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Revenue$301.7M+48.3%
Gross profit$196.7M+52.8%
Operating income-$121.4M-9.3%
Net income-$112.1M-17.8%
EPS (diluted)-$0.85-10.4%

Balance sheet

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Cash & equivalents$1.1B+37.0%
Total debt$1.7B+30.5%
Total equity-$181.1M+27.8%
Total assets$1.9B+42.5%

Cash flow

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Operating cash flow-$65.6M-4.7%
CapEx$5.6M+25.1%
Free cash flow-$71.2M-6.0%

Valuation

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Market cap$17.12B+130%
Enterprise value$17.72B+121%
P/S15.9×+6.3×

Profitability

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Gross margin64.9%+3.6pp
Net margin-40.1%-8.1pp

Returns & leverage

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Return on equity-438.1%-1,655pp
Debt / equity
Current ratio4.7×+0.6×

Where this comes from

Calculated from Guardant Health’s reported figures.

Based on trailing twelve months.

The official record: Guardant Health’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Guardant Health's operating margin?
Guardant Health (GH) reported operating margin of -41.4% in Q1 2026.
How has Guardant Health's operating margin changed year-over-year?
Guardant Health's operating margin increased by 29.5% year-over-year, from -58.8% to -41.4%.
What is the long-term trend for Guardant Health's operating margin?
Over 4 years (2021 to 2025), Guardant Health's operating margin has grown at a -17.7% compound annual growth rate (CAGR), from -452.2% to -207.9%.
What does operating margin mean?
The profit left from core operations for every dollar of sales, before interest and taxes.
How do you interpret operating margin?
Expanding operating margin shows operating leverage — revenue growing faster than the cost base. Compression points to rising overhead, pricing pressure, or investment ahead of revenue.
How does operating margin compare across companies?
Strong cross-company signal within a sector. Capital-light businesses sustain higher operating margins than capital-intensive ones.