Operating Income
Operating Income
Guardant Health Operating Income decreased by 0.5% to -$121.35M in Q1 2026 compared to the prior quarter. Year-over-year, this metric declined by 9.3%, from -$111.04M to -$121.35M. Over 4 years (FY 2021 to FY 2025), Operating Income shows relatively stable performance with a 1.6% CAGR. This decline may warrant attention — for this metric, higher values are generally preferred.
Analysis
StatementIncome Statement
SectionOperating Income
CategoryProfitability
SignalHigher is better
VolatilityVolatile
First reportedQ1 2016
Last reportedQ1 2026May 7, 2026
How to read this metric
A positive and growing operating income indicates a healthy, self-sustaining business model.
Detailed definition
Operating income is the profit realized from core business operations after deducting all operating expenses from gross...
Peer comparison
Often negative for high-growth biotech firms; investors focus on the trend toward positive territory.
Metric ID:
operating_incomeHistorical Data
20 periods
| Q2 '21 | Q3 '21 | Q4 '21 | Q1 '22 | Q2 '22 | Q3 '22 | Q4 '22 | Q1 '23 | Q2 '23 | Q3 '23 | Q4 '23 | Q1 '24 | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Value | -$97.64M | -$107.29M | -$98.21M | -$123.34M | -$130.32M | -$144.6M | -$146.12M | -$134.06M | -$119.62M | -$113.54M | -$197.51M | -$99.68M | -$100.62M | -$117.33M | -$125.97M | -$111.04M | -$106.41M | -$98.99M | -$120.81M | -$121.35M |
| QoQ Change | — | -9.9% | +8.5% | -25.6% | -5.7% | -11.0% | -1.1% | +8.3% | +10.8% | +5.1% | -74.0% | +49.5% | -0.9% | -16.6% | -7.4% | +11.8% | +4.2% | +7.0% | -22.0% | -0.5% |
| YoY Change | — | — | — | — | -33.5% | -34.8% | -48.8% | -8.7% | +8.2% | +21.5% | -35.2% | +25.6% | +15.9% | -3.3% | +36.2% | -11.4% | -5.8% | +15.6% | +4.1% | -9.3% |
Range-$197.51M – -$97.64M
CAGR+4.7%
Avg YoY Growth-4.0%
Median YoY Growth-4.5%
Current Streak2 quarters decline
Operating Income at Other Companies
Frequently Asked Questions
- What is Guardant Health's operating income?
- Guardant Health (GH) reported operating income of -$121.35M in Q1 2026.
- How has Guardant Health's operating income changed year-over-year?
- Guardant Health's operating income decreased by 9.3% year-over-year, from -$111.04M to -$121.35M.
- What is the long-term trend for Guardant Health's operating income?
- Over 4 years (2021 to 2025), Guardant Health's operating income has grown at a 1.6% compound annual growth rate (CAGR), from -$411M to -$437.25M.
- What does operating income mean?
- Profit earned from core business operations before interest and taxes.