What is Illumina's operating income?

Illumina (ILMN) reported operating income of $209M in Q1 2026.

How has Illumina's operating income changed year-over-year?

Illumina's operating income increased by 27.4% year-over-year, from $164M to $209M.

What is the long-term trend for Illumina's operating income?

Over 2 years (2022 to 2025), Illumina's operating income has grown at a -56.1% compound annual growth rate (CAGR), from -$4.18B to $806M.

What does operating income mean?

Gross profit minus all operating expenses (SG&A, R&D, D&A). Measures the profit from core business operations before interest, taxes, and non-operating items.

Illumina ILMN Operating Income

Operating Income at other companies

RevvityRVTY

$75.89M+5.1%

Thermo Fisher ScientificTMO

$1.86B+8.6%

AzentaAZTA

-$165.79M-811%

Personalis, Inc.PSNL

-$32.16M-81.7%

Guardant HealthGH

-$121.35M-9.3%

Twist Bioscience CorporationTWST

-$45.86M-10.4%

Other financials

Income statement

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Revenue$1.1B+4.8%

Gross profit$721.0M+5.6%

Net income$134.0M+2.3%

EPS (diluted)$0.87+6.1%

Balance sheet

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Cash & equivalents$1.1B-2.2%

Total debt$2.0B-3.0%

Total equity$2.7B+13.0%

Total assets$6.6B+6.1%

Cash flow

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Operating cash flow$289.0M+20.4%

CapEx$38.0M+18.8%

Free cash flow$251.0M+20.7%

Valuation

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Market cap$26.6B+91.5%

Enterprise value$27.56B+83.6%

P/E31.2×+20.1×

P/S6.1×+2.8×

Profitability

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Gross margin66.2%-0.1pp

Operating margin19.4%—

Net margin19.4%+12.7pp

FCF margin22.2%+2.0pp

Returns & leverage

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Return on equity33.8%+23.9pp

Debt / equity0.8×-0.1×

Current ratio1.7×-0.1×

Where this comes from

Reported directly by Illumina in its filing.

Tagged under the XBRL concept us-gaap:OperatingIncomeLoss.

The official record: Illumina’s 10-Q, filed May 4, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Illumina's operating income?: Illumina (ILMN) reported operating income of $209M in Q1 2026.
How has Illumina's operating income changed year-over-year?: Illumina's operating income increased by 27.4% year-over-year, from $164M to $209M.
What is the long-term trend for Illumina's operating income?: Over 2 years (2022 to 2025), Illumina's operating income has grown at a -56.1% compound annual growth rate (CAGR), from -$4.18B to $806M.
What does operating income mean?: Gross profit minus all operating expenses (SG&A, R&D, D&A). Measures the profit from core business operations before interest, taxes, and non-operating items.