What is Illumina's gross profit?

Illumina (ILMN) reported gross profit of $721M in Q1 2026.

How has Illumina's gross profit changed year-over-year?

Illumina's gross profit increased by 5.6% year-over-year, from $683M to $721M.

What is the long-term trend for Illumina's gross profit?

Over 4 years (2021 to 2025), Illumina's gross profit has grown at a -2.3% compound annual growth rate (CAGR), from $3.15B to $2.87B.

What does gross profit mean?

Revenue minus cost of revenue — the profit available to cover operating expenses, representing the company's pricing power and production efficiency.

Illumina ILMN Gross Profit

Gross Profit at other companies

AzentaAZTA

$62.04M-1.2%

Personalis, Inc.PSNL

$281K-96.1%

Twist Bioscience CorporationTWST

$57.12M+24.1%

10x Genomics, Inc.TXG

$106.18M+0.7%

RevvityRVTY

——

Guardant HealthGH

——

Other financials

Income statement

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Revenue$1.1B+4.8%

Operating income$209.0M+27.4%

Net income$134.0M+2.3%

EPS (diluted)$0.87+6.1%

Balance sheet

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Cash & equivalents$1.1B-2.2%

Total debt$2.0B-3.0%

Total equity$2.7B+13.0%

Total assets$6.6B+6.1%

Cash flow

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Operating cash flow$289.0M+20.4%

CapEx$38.0M+18.8%

Free cash flow$251.0M+20.7%

Valuation

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Market cap$26.6B+91.5%

Enterprise value$27.56B+83.6%

P/E31.2×+20.1×

P/S6.1×+2.8×

Profitability

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Gross margin66.2%-0.1pp

Operating margin19.4%—

Net margin19.4%+12.7pp

FCF margin22.2%+2.0pp

Returns & leverage

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Return on equity33.8%+23.9pp

Debt / equity0.8×-0.1×

Current ratio1.7×-0.1×

Where this comes from

Calculated from Illumina’s reported figures.

$1.1Btotal revenue−$370.0Mtotal cost of revenue=$721M

The official record: Illumina’s 10-Q, filed May 4, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Illumina's gross profit?: Illumina (ILMN) reported gross profit of $721M in Q1 2026.
How has Illumina's gross profit changed year-over-year?: Illumina's gross profit increased by 5.6% year-over-year, from $683M to $721M.
What is the long-term trend for Illumina's gross profit?: Over 4 years (2021 to 2025), Illumina's gross profit has grown at a -2.3% compound annual growth rate (CAGR), from $3.15B to $2.87B.
What does gross profit mean?: Revenue minus cost of revenue — the profit available to cover operating expenses, representing the company's pricing power and production efficiency.