What is GRAIL, Inc.'s net margin?

GRAIL, Inc. (GRAL) reported net margin of -253.2% in Q1 2026.

How has GRAIL, Inc.'s net margin changed year-over-year?

GRAIL, Inc.'s net margin increased by 82.7% year-over-year, from -1,464.5% to -253.2%.

What is the long-term trend for GRAIL, Inc.'s net margin?

Over 3 years (2022 to 2025), GRAIL, Inc.'s net margin has grown at a -69.4% compound annual growth rate (CAGR), from -9,719.3% to -277.5%.

What does net margin mean?

Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.

GRAIL, Inc. GRAL Net margin

Net margin at other companies

AbbottABT

13.9%-18.0pp

Guardant HealthGH

-40.1%-8.1pp

Natera, Inc.NTRA

-14.6%+0.6pp

Tempus AI, Inc.TEM

-22.2%-9.5pp

ImmunomeIMNM

-5,593.8%-11,284pp

Adaptive BiotechnologiesADPT

-16.8%-7.3pp

Other financials

Income statement

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Revenue$40.8M+28.1%

Operating income-$135.8M+11.6%

Net income-$93.2M+12.3%

EPS (diluted)-$2.29+26.1%

Balance sheet

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Cash & equivalents$76.3M-44.4%

Total debt$51.0M-20.7%

Total equity$2.5B+3.6%

Total assets$2.8B-1.5%

Cash flow

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Operating cash flow-$87.0M+8.4%

CapEx$503.0K+711%

Free cash flow-$87.5M+8.0%

Valuation

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Market cap$2.62B+145%

Enterprise value$2.6B+164%

P/S16.8×+8.6×

Profitability

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Operating margin-348.7%-153pp

FCF margin-187.2%-60.4pp

Returns & leverage

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Return on equity-16.1%—

Debt / equity0×0.0×

Current ratio11.7×+2.0×

Where this comes from

Calculated from GRAIL, Inc.’s reported figures.

net income/total revenue=-253.2%

Based on trailing twelve months.

The official record: GRAIL, Inc.’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is GRAIL, Inc.'s net margin?: GRAIL, Inc. (GRAL) reported net margin of -253.2% in Q1 2026.
How has GRAIL, Inc.'s net margin changed year-over-year?: GRAIL, Inc.'s net margin increased by 82.7% year-over-year, from -1,464.5% to -253.2%.
What is the long-term trend for GRAIL, Inc.'s net margin?: Over 3 years (2022 to 2025), GRAIL, Inc.'s net margin has grown at a -69.4% compound annual growth rate (CAGR), from -9,719.3% to -277.5%.
What does net margin mean?: Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.