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Insmed INSM EBITDA margin

EBITDA margin at other companies

United Therapeutics logo
United TherapeuticsUTHR
48.1%-1.4pp
Incyte logo
IncyteINCY
31.8%+25.8pp
Amgen logo
AmgenAMGN
41.5%+3.4pp
ALN
Alnylam PharmaceuticalsALNY
18.8%+16.9pp
Neurocrine Biosciences logo
Neurocrine BiosciencesNBIX
26.4%+4.7pp
Johnson & Johnson logo
Johnson & JohnsonJNJ
34.4%+2.7pp

Other financials

Income statement

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Revenue$306.0M+230%
Gross profit$258.5M+261%
Operating income-$153.3M+38.2%
Net income-$163.6M+36.3%
EPS (diluted)-$0.76+46.5%

Balance sheet

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Cash & equivalents$582.2M+44.4%
Total debt$580.3M-49.2%
Total equity$704.9M+611%
Total assets$2.1B+15.2%

Cash flow

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Operating cash flow-$222.7M+15.0%
CapEx$3.5M-65.4%
Free cash flow-$226.2M+16.9%

Valuation

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Market cap$20.76B+155%
Enterprise value$20.76B+142%
P/S25.3×+4.0×

Profitability

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Gross margin81.8%+5.3pp
Operating margin-140.6%-43.9pp
Net margin-144.4%-45.3pp
FCF margin-112.5%-35.3pp

Returns & leverage

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Return on equity-294.5%
Debt / equity0.8×-10.7×
Current ratio4.5×-1.4×

Where this comes from

Calculated from Insmed’s reported figures.

Based on trailing twelve months.

The official record: Insmed’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Insmed's EBITDA margin?
Insmed (INSM) reported EBITDA margin of -138.3% in Q1 2026.
How has Insmed's EBITDA margin changed year-over-year?
Insmed's EBITDA margin increased by 45.6% year-over-year, from -254.5% to -138.3%.
What is the long-term trend for Insmed's EBITDA margin?
Over 5 years (2020 to 2025), Insmed's EBITDA margin has grown at a 5.4% compound annual growth rate (CAGR), from -155.8% to -202.9%.
What does EBITDA margin mean?
Operating cash profitability per sales dollar, before interest, taxes, and non-cash charges.
How do you interpret EBITDA margin?
Useful for comparing operating profitability across firms with different depreciation policies and leverage. High EBITDA margin alongside heavy capex can still mean weak free cash flow — pair it with FCF margin.
How does EBITDA margin compare across companies?
Widely used to compare capital-intensive businesses on a like-for-like basis. Less meaningful for banks and insurers.