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Iovance Biotherapeutics, Inc.

IOVA

Iovance Biotherapeutics is a commercial-stage biopharmaceutical company specializing in the development and delivery of tumor infiltrating lymphocyte (TIL) cell therapies for solid tumor cancers.

Market cap
$2.19B+145%
Revenue$285.6M+34.3%
Net income-$353.9M+5.7%
Free cash flow-$305.0M+12.2%
EPS (diluted)-$1.13+24.2%
Trailing twelve months · change vs. prior year

Earnings

Next report

Aug 6, 2026 (In 1 week)
Revenue estimate$87.7M
EPS estimate-$0.17

Financials

Q1 2026

Income statement

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Revenue$71.4M+44.8%
Gross profit$28.9M+338%
Operating income-$81.0M+33.1%
Net income-$79.0M+32.0%
EPS (diluted)-$0.19+47.2%

Balance sheet

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Cash & equivalents$196.5M+14.5%
Total debt$46.8M-11.3%
Total equity$721.8M-6.0%
Total assets$925.7M-4.2%

Cash flow

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Operating cash flow-$72.1M+30.5%
CapEx$6.6M+6.4%
Free cash flow-$78.7M+28.4%

Valuation & ratios

Valuation

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Market cap$2.19B+145%
Enterprise value$2.04B+125%
P/S7.7×+3.6×

Profitability

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Gross margin36.7%+4.1pp
Operating margin-127.2%-31.0pp
Net margin-123.9%-28.4pp
FCF margin-106.8%-27.5pp

Returns & leverage

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Return on equity-47.5%-3.7pp
Debt / equity0.1×0.0×
Current ratio3.6×-0.6×

Segments

By product

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Amtagvi$60.2M+38.2%
Proleukin$11.2M+94.8%

By segment

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Single Reportable$71.4M+44.8%

Competitors

Profile

Iovance Biotherapeutics is a commercial-stage biopharmaceutical company specializing in the development and delivery of tumor infiltrating lymphocyte (TIL) cell therapies for solid tumor cancers. The company utilizes a proprietary manufacturing process to create individualized, polyclonal T cell therapies that harness a patient's own immune system to recognize and destroy cancer cells. Their platform transforms complex research-based cell therapies into scalable, commercially accessible treatments for advanced cancer patients.

Competitive position

Pioneer in the first FDA-approved one-time T cell therapy for solid tumor cancers, transitioning from a research-focused entity to a commercial-stage leader in TIL technology.

GeographiesUnited States, Canada, United Kingdom, Australia, Switzerland, European Union
Customer segmentsAdvanced Melanoma Patients, Specialized Oncology Centers, Healthcare Payors
Business modelIndividualized Cell Therapy Manufacturing, Biopharmaceutical Research and Development
SuppliersPatient Tissue Collection, Specialized Cell Culture Media, Manufacturing Equipment Providers, Logistics and Cold Chain Services
CustomersAuthorized Treatment Centers, Specialty Pharmacies, Government and Private Health Insurers
Listed2010
Employees557.0
CEOFrederick G. Vogt
FilingsSEC EDGAR

Questions, answered.

What is Iovance Biotherapeutics, Inc.'s market cap?
Iovance Biotherapeutics, Inc. (IOVA) has a market capitalization of $2.2B and trades on NASDAQ.
What is Iovance Biotherapeutics, Inc.'s revenue and profitability?
Iovance Biotherapeutics, Inc. generated $285.6M in trailing twelve-month revenue with a net loss of $353.9M, representing a net margin of -123.9%. Gross margin stands at 36.7%, with free cash flow of -$305.0M. These figures are based on the Q1 2026 filing.
Who are Iovance Biotherapeutics, Inc.'s competitors?
Iovance Biotherapeutics, Inc.'s key competitors include Bristol-Myers Squibb, Gilead Sciences, Citius Oncology, Inc. Common Stock, and others. These companies compete in similar markets and product categories.
Who does Iovance Biotherapeutics, Inc. partner with?
Iovance Biotherapeutics, Inc.'s notable partners include National Cancer Institute, European Medicines Agency.
Where is Iovance Biotherapeutics, Inc. headquartered?
Iovance Biotherapeutics, Inc. is headquartered in United States of America and employs approximately 557 people. It has been publicly traded since 2010.