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Krystal Biotech, Inc.

KRYS

Krystal Biotech is a commercial-stage biotechnology company specializing in the development and commercialization of genetic medicines for rare and serious diseases.

Market cap
$10.37B+134%
Revenue$417.3M+25.2%
Net income$225.0M+81.5%
Free cash flow$237.4M+76.3%
EPS (diluted)$7.48+79.4%
Trailing twelve months · change vs. prior year

Earnings

Next report

Aug 3, 2026 (In 5 days)
Revenue estimate$121.8M
EPS estimate$1.70

Financials

Q1 2026

Income statement

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Revenue$116.4M+31.9%
Operating income$53.7M+48.1%
Net income$55.9M+56.5%
EPS (diluted)$1.83+52.5%

Balance sheet

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Cash & equivalents$501.3M+62.4%
Total debt$9.1M-5.7%
Total equity$1.3B+29.7%
Total assets$1.4B+30.0%

Cash flow

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Operating cash flow$80.4M+160%
CapEx$7.1M+15.2%
Free cash flow$73.2M+196%

Valuation & ratios

Valuation

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Market cap$10.37B+134%
Enterprise value$9.88B+142%
P/E46.1×+16.0×
P/S24.9×+12.5×

Profitability

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Operating margin42.8%+10.2pp
Net margin53.9%+16.7pp
FCF margin56.9%+16.5pp

Returns & leverage

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Return on equity19.9%+6.0pp
Debt / equity0.0×
Current ratio9.5×-0.2×

Segments

By geography

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Europe$20.7M

Competitors

Profile

Krystal Biotech is a commercial-stage biotechnology company specializing in the development and commercialization of genetic medicines for rare and serious diseases. The company utilizes a proprietary gene therapy platform based on engineered herpes simplex virus-1 (HSV-1) to deliver therapeutic transgenes through non-invasive or minimally invasive administration. Their integrated model encompasses discovery, clinical development, and in-house commercial-scale CGMP manufacturing.

Competitive position

Krystal Biotech is a leader in redosable gene therapy with the first-ever FDA-approved topical gene therapy and maintains a competitive advantage through vertically integrated manufacturing.

GeographiesUnited States, European Union, Japan, Global
Customer segmentsRare disease patients, Specialized healthcare professionals, Oncology patients
Business modelR&D intensive manufacturing, Direct-to-market pharmaceutical sales, Intellectual property licensing
SuppliersRaw material suppliers for CGMP manufacturing, Clinical research organizations, Laboratory equipment providers
CustomersSpecialty pharmacies, Dermatology clinics, Medical distributors, Health insurance payers
Listed2017
Employees229.0
CEOKrish S. Krishnan
FilingsSEC EDGAR

Questions, answered.

What is Krystal Biotech, Inc.'s market cap?
Krystal Biotech, Inc. (KRYS) has a market capitalization of $10.4B and trades on NASDAQ.
What is Krystal Biotech, Inc.'s revenue and profitability?
Krystal Biotech, Inc. generated $417.3M in trailing twelve-month revenue with net income of $225.0M, representing a net margin of 53.9%, with free cash flow of $237.4M. These figures are based on the Q1 2026 filing.
Who are Krystal Biotech, Inc.'s competitors?
Krystal Biotech, Inc.'s key competitors include Abeona Therapeutics, Sarepta Therapeutics, Soligenix, Inc. Common Stock, and others. These companies compete in similar markets and product categories.
What subsidiaries does Krystal Biotech, Inc. have?
Krystal Biotech, Inc.'s subsidiaries include Jeune Aesthetics, Inc..
Where is Krystal Biotech, Inc. headquartered?
Krystal Biotech, Inc. is headquartered in United States of America and employs approximately 229 people. It has been publicly traded since 2017.