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Discontinued — last reported Q4 '25

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Other financials

Income statement

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Revenue$692.0K-97.6%
Gross profit$653.0K-97.7%
Operating income-$26.5M-810%
Net income-$31.8M-1,077%
EPS (diluted)-$0.07-800%

Balance sheet

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Cash & equivalents$40.9M-18.7%
Total debt$59.2M-3.6%
Total equity$174.5M+34.8%
Total assets$250.1M+10.9%

Cash flow

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Operating cash flow-$9.2M
Free cash flow-$17.2M+21.5%

Valuation

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Market cap$1.1B+191%
Enterprise value$1.12B+187%
P/S26.5×+20.0×

Profitability

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Gross margin99.1%0.0pp
Operating margin-131.4%-34.2pp
Net margin-147.4%-32.8pp
FCF margin-578.5%-283pp

Returns & leverage

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Return on equity-40.2%-11.2pp
Debt / equity0.3×-0.1×
Current ratio13.4×+9.2×

Where this comes from

Reported directly by Lexicon Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:PaymentsToAcquirePropertyPlantAndEquipment.

The source filing: Lexicon Pharmaceuticals’s 10-K, filed March 5, 2026.

Filed
Mar 5, 2026, 4:50 PM EST
Fiscal year
FY2025
Accession
0001062822-26-000050
Line itemYear Ended December 31, 2025Year Ended December 31, 2024Year Ended December 31, 2023
(Decrease) increase in accounts payable and other liabilities(30,222)14,8016,454
Net cash used in operating activities(67,851)(178,780)(161,897)
Cash flows from investing activities:
Purchases of property and equipment(1,031)(470)
Purchases of investments(139,838)(328,747)(223,343)
Maturities of investments252,858314,400173,870
Net cash provided by (used in) investing activities113,020(15,378)(49,943)
Cash flows from financing activities:

Item 16. Form 10-K Summary

FAQ

What is Lexicon Pharmaceuticals's capex?
Lexicon Pharmaceuticals (LXRX) reported capex of $0 in Q4 2025.
How has Lexicon Pharmaceuticals's capex changed year-over-year?
Lexicon Pharmaceuticals's capex decreased by 100.0% year-over-year, from $474K to $0.
What is the long-term trend for Lexicon Pharmaceuticals's capex?
Over 3 years (2021 to 2024), Lexicon Pharmaceuticals's capex has grown at a -5.5% compound annual growth rate (CAGR), from $1.22M to $1.03M.
What does capex mean?
Cash spent on property, plant, and equipment — the primary measure of investment in productive capacity and infrastructure.

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