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Oruka Therapeutics, Inc.

ORKA

Oruka Therapeutics is a clinical-stage biopharmaceutical company dedicated to developing novel monoclonal antibody therapeutics for chronic inflammatory and immunology indications, with a primary focus on psoriasis and related skin diseases.

Market cap
$5.94B+934%
Net income-$116.3M+25.3%
Free cash flow-$91.2M+23.6%
Trailing twelve months · change vs. prior year

Earnings

Next report

Aug 10, 2026 (Tomorrow)
EPS estimate-$0.51

Financials

Q1 2026

Income statement

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Operating income-$36.4M-45.2%
Net income-$31.8M-51.5%

Balance sheet

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Cash & equivalents$49.5M-40.7%
Total debt$1.8M+90.8%
Total equity$486.7M+33.4%
Total assets$504.5M+33.8%

Cash flow

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Operating cash flow-$23.6M-13.0%
CapEx$73.0K+462%
Free cash flow-$23.7M-13.3%

Valuation & ratios

Valuation

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Market cap$5.94B+934%
Enterprise value$5.89B+1,158%

Returns & leverage

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Return on equity-27.3%-11.1pp
Debt / equity0.0×
Current ratio23.8×-6.3×

Competitors

Profile

Oruka Therapeutics is a clinical-stage biopharmaceutical company dedicated to developing novel monoclonal antibody therapeutics for chronic inflammatory and immunology indications, with a primary focus on psoriasis and related skin diseases. The company leverages antibody engineering and half-life extension technologies to optimize validated modes of action, aiming to provide superior efficacy and significantly less frequent dosing compared to current standard-of-care treatments.

Competitive position

A clinical-stage challenger focused on improving the dosing frequency and efficacy of established biologic classes through advanced antibody engineering.

GeographiesUnited States, Global
Customer segmentsPatients, Healthcare providers
Business modelR&D intensive, IP licensing
SuppliersAntibody discovery engines, Contract Manufacturing Organizations (CMOs), Clinical Research Organizations (CROs), Specialized cell line providers
CustomersSpecialty pharmacies, Hospitals, Dermatology clinics, Rheumatology clinics
Listed2024
CEOLawrence Otto Klein
FilingsSEC EDGAR

FAQ

What is Oruka Therapeutics, Inc.'s market cap?
Oruka Therapeutics, Inc. (ORKA) has a market capitalization of $5.9B and trades on XNAS.
Who are Oruka Therapeutics, Inc.'s competitors?
Oruka Therapeutics, Inc.'s key competitors include Eli Lilly, AbbVie, Johnson & Johnson, and others. These companies compete in similar markets and product categories.
Who does Oruka Therapeutics, Inc. partner with?
Oruka Therapeutics, Inc.'s notable partners include Paragon Therapeutics, Inc., WuXi Biologics Ireland Limited, Fairmount Funds Management LLC.
What subsidiaries does Oruka Therapeutics, Inc. have?
Oruka Therapeutics, Inc.'s subsidiaries include Oruka Therapeutics Operating Company, LLC.
Where is Oruka Therapeutics, Inc. headquartered?
Oruka Therapeutics, Inc. is headquartered in United States of America. It has been publicly traded since 2024.