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Discontinued — last reported Q4 '25

Total debt at other companies

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Ionis PharmaceuticalsIONS
$691.72M+334%
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Arrowhead ResearchARWR
$107.88M-5.6%
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CRISPR TherapeuticsCRSP
$787.64M+259%
Eli Lilly logo
Eli LillyLLY
Amgen logo
AmgenAMGN
Moderna logo
ModernaMRNA

Other financials

Income statement

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Revenue$136.0M-2.2%
Operating income-$169.0M-18.2%
Net income-$185.0M-22.5%
EPS (diluted)-$1.84-17.2%

Balance sheet

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Cash & equivalents$175.0M+37.8%
Total equity-$236.0M-264%
Total assets$1.3B-1.2%

Cash flow

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Operating cash flow-$197.0M-18.7%
CapEx$1.0M0.0%
Free cash flow-$198.0M-18.6%

Valuation

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Market cap$2.83B-39.4%
P/S4.2×-3.7×

Profitability

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Gross margin97.2%
Operating margin-83.8%-3.0pp
Net margin-90.9%-2.1pp
FCF margin-75.1%+10.7pp

Returns & leverage

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Return on equity-325.6%+36.9pp
Debt / equity3.7×
Current ratio-0.4×

Where this comes from

Computed from long term debt + current portion long term debt + short term borrowings + operating lease liabilities + finance lease liabilities + financing obligations: $36M.

The official record: Ultragenyx Pharmaceutical’s 10-K, filed February 18, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Ultragenyx Pharmaceutical's total debt?
Ultragenyx Pharmaceutical (RARE) reported total debt of $36M in Q4 2025.
How has Ultragenyx Pharmaceutical's total debt changed year-over-year?
Ultragenyx Pharmaceutical's total debt decreased by 10.8% year-over-year, from $40.34M to $36M.
What is the long-term trend for Ultragenyx Pharmaceutical's total debt?
Over 5 years (2020 to 2025), Ultragenyx Pharmaceutical's total debt has grown at a -5.7% compound annual growth rate (CAGR), from $48.23M to $36M.
What does total debt mean?
Total debt represents the aggregate sum of all interest-bearing financial obligations, including short-term borrowings, the current portion of long-term debt, and long-term debt instruments. It also encompasses capitalized lease liabilities and other debt-like financing arrangements that require fixed repayment schedules. This metric serves as a comprehensive indicator of a company's total financial leverage and its reliance on external capital providers.