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Other financials

Income statement

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Revenue$64.9M+224%
Operating income-$34.2M+59.2%
Net income-$42.7M+49.7%
EPS (diluted)-$0.48+51.0%

Balance sheet

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Cash & equivalents$130.9M-15.0%
Total debt$350.5M+4.2%
Total equity$41.6M-80.6%
Total assets$472.7M-26.2%

Cash flow

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Operating cash flow-$50.3M+47.1%
CapEx$46.8K
Free cash flow-$80.8M-17.6%

Valuation

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Market cap$1.76B+58.9%
Enterprise value$1.98B+48.9%
P/S8.1×-6.1×

Profitability

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Operating margin-102.8%-47.8pp
Net margin-111.9%-51.5pp
FCF margin-187.2%-85.4pp

Returns & leverage

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Return on equity-189.5%-8,509pp
Debt / equity8.4×+6.9×
Current ratio5.5×-0.3×

Where this comes from

Reported directly by Syndax Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:SellingGeneralAndAdministrativeExpense.

The source filing: Syndax Pharmaceuticals’s 10-K, filed February 26, 2026.

Filed
Feb 26, 2026, 4:04 PM EST
Fiscal year
FY2025
Accession
0001193125-26-076536
Line itemYears Ended December 31, 2025Years Ended December 31, 2024Years Ended December 31, 2023
Operating expenses:
Cost of product sales6,970826
Research and development258,784241,647163,032
Selling, general and administrative179,682120,87966,922
Total operating expenses445,436363,352229,954
Loss from operations(273,084)(339,672)(229,954)
Other (expense) income, net:
Royalty interest expense(33,779)(4,930)

Item 16. Form 10-K Summary

FAQ

What is Syndax Pharmaceuticals's SG&A?
Syndax Pharmaceuticals (SNDX) reported SG&A of $44.92M in Q4 2025.
How has Syndax Pharmaceuticals's SG&A changed year-over-year?
Syndax Pharmaceuticals's SG&A increased by 48.6% year-over-year, from $30.22M to $44.92M.
What is the long-term trend for Syndax Pharmaceuticals's SG&A?
Over 4 years (2021 to 2025), Syndax Pharmaceuticals's SG&A has grown at a 63.3% compound annual growth rate (CAGR), from $25.24M to $179.68M.
What does SG&A mean?
Combined selling expenses (sales force, marketing, distribution) and general & administrative costs (management, legal, accounting, facilities) — the broadest opex category.

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