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Operating margin at other companies

Ionis Pharmaceuticals logo
Ionis PharmaceuticalsIONS
-33.3%-11.0pp
Acadia Pharmaceuticals logo
Acadia PharmaceuticalsACAD
7.4%-16.2pp
Ultragenyx Pharmaceutical logo
Ultragenyx PharmaceuticalRARE
-83.8%-3.0pp
uniQure logo
uniQureQURE
-1,059.7%+380pp
Precigen logo
PrecigenPGEN
-2,890.9%
Stoke Therapeutics, Inc. logo
Stoke Therapeutics, Inc.STOK
-577.5%-597pp

Other financials

Income statement

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Revenue--100%
Operating income-$43.5M-103%
Net income-$42.4M-97.0%
EPS (diluted)-$0.12-50.0%

Balance sheet

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Cash & equivalents$276.6M+137%
Total debt$68.6M+11.2%
Total equity$211.9M+285%
Total assets$300.4M+117%

Cash flow

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Operating cash flow-$40.9M-85.6%
CapEx$24.0K-93.7%
Free cash flow-$40.9M-82.6%

Valuation

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Market cap$1.97B+351%
Enterprise value$1.76B+368%
P/S263.9×+203×

Profitability

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Net margin-1,738.4%+1,407pp
FCF margin-1,503.6%+621pp

Returns & leverage

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Return on equity-97.3%-27.3pp
Debt / equity0.3×-0.8×
Current ratio14×+8.7×

Where this comes from

Calculated from Taysha Gene Therapies, Inc.’s reported figures.

Based on trailing twelve months.

The official record: Taysha Gene Therapies, Inc.’s 10-Q, filed May 6, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Taysha Gene Therapies, Inc.'s operating margin?
Taysha Gene Therapies, Inc. (TSHA) reported operating margin of -1,774.4% in Q1 2026.
How has Taysha Gene Therapies, Inc.'s operating margin changed year-over-year?
Taysha Gene Therapies, Inc.'s operating margin decreased by 44.8% year-over-year, from -1,225.8% to -1,774.4%.
What is the long-term trend for Taysha Gene Therapies, Inc.'s operating margin?
Over 3 years (2022 to 2025), Taysha Gene Therapies, Inc.'s operating margin has grown at a -44.2% compound annual growth rate (CAGR), from -6,492.7% to -1,130.6%.
What does operating margin mean?
Operating income as a percentage of revenue (trailing twelve months). Captures profitability from core operations after both cost of revenue and operating expenses, but before interest and taxes.