Ionis Pharmaceuticals IONS Operating margin

Operating margin at other companies

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ALN

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20.8%+16.5pp

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FAQ

What is Ionis Pharmaceuticals's operating margin?

Ionis Pharmaceuticals (IONS) reported operating margin of -68% in Q2 2026.

How has Ionis Pharmaceuticals's operating margin changed year-over-year?

Ionis Pharmaceuticals's operating margin decreased by 140.9% year-over-year, from -28.2% to -68%.

What is the long-term trend for Ionis Pharmaceuticals's operating margin?

Over 5 years (2020 to 2025), Ionis Pharmaceuticals's operating margin has grown at a 11.4% compound annual growth rate (CAGR), from -23.6% to -40.4%.

What does operating margin mean?

Operating income as a percentage of revenue (trailing twelve months). Captures profitability from core operations after both cost of revenue and operating expenses, but before interest and taxes.