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Debt-to-equity at other companies

Eli Lilly logo
Eli LillyLLY
1.6×-0.6×
Pfizer logo
PfizerPFE
0.7×0.0×
Arrowhead Research logo
Arrowhead ResearchARWR
0.2×0.0×
ALN
Alnylam PharmaceuticalsALNY
0.2×-0.9×
Ultragenyx Pharmaceutical logo
Ultragenyx PharmaceuticalRARE
3.7×
Stoke Therapeutics, Inc. logo
Stoke Therapeutics, Inc.STOK
0.0×

Other financials

Income statement

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Revenue$267.9M-40.7%
Gross profit$265.2M-40.8%
Operating income-$102.3M-173%
Net income-$114.6M-193%
EPS (diluted)-$0.69-199%

Balance sheet

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Cash & equivalents$350.1M+17.7%
Total debt$262.5M-67.0%
Total equity$439.7M-30.4%
Total assets$3.0B+0.3%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$16.1M+30.7%
Free cash flow-$814.6M-399%

Valuation

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Market cap$9.01B+38.9%
Enterprise value$8.92B+27.7%
P/S10.3×+3.4×

Profitability

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Gross margin98.2%-0.7pp
Operating margin-68%-234pp
Net margin-64.7%-299pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-105.5%+336pp
Current ratio7.9×+5.0×

Where this comes from

Calculated from Ionis Pharmaceuticals’s reported figures.

Based on the most recent quarter.

The source filing: Ionis Pharmaceuticals’s 10-Q, filed July 29, 2026. Open the filing →

Filed
Jul 29, 2026, 5:05 PM EDT
Fiscal quarter
Q2 FY2026
Calendar quarter
Q2 2026
Accession
0000874015-26-000251

FAQ

What is Ionis Pharmaceuticals's debt-to-equity?
Ionis Pharmaceuticals (IONS) reported debt-to-equity of 0.6× in Q2 2026.
How has Ionis Pharmaceuticals's debt-to-equity changed year-over-year?
Ionis Pharmaceuticals's debt-to-equity decreased by 52.5% year-over-year, from 1.3× to 0.6×.
What is the long-term trend for Ionis Pharmaceuticals's debt-to-equity?
Over 5 years (2020 to 2025), Ionis Pharmaceuticals's debt-to-equity has grown at a 62.9% compound annual growth rate (CAGR), from 0.4× to 5×.
What does debt-to-equity mean?
Total debt (including capitalized leases and financing obligations) divided by shareholders' equity at the quarter end. Measures how much the company is financed by debt relative to equity.

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