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Net margin at other companies

Eli Lilly logo
Eli LillyLLY
35%+12.3pp
Pfizer logo
PfizerPFE
15.7%
Arrowhead Research logo
Arrowhead ResearchARWR
-48.4%+240pp
ALN
Alnylam PharmaceuticalsALNY
11.7%+8.0pp
BridgeBio Pharma logo
BridgeBio PharmaBBIO
-125.9%-54.5pp
Neurocrine Biosciences logo
Neurocrine BiosciencesNBIX
21.6%+8.9pp

Other financials

Income statement

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Revenue$246.1M+87.0%
Gross profit$243.1M+86.8%
Operating income-$117.4M+20.0%
Net income-$92.5M+37.0%
EPS (diluted)-$0.56+39.8%

Balance sheet

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Cash & equivalents$173.4M-34.4%
Total debt$691.7M+334%
Total equity$491.4M+3.3%
Total assets$3.4B+22.6%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$21.8M+73.0%
Free cash flow-$814.6M-399%

Valuation

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Market cap$12.25B+159%
Enterprise value$12.77B+175%
P/S11.6×+5.0×

Profitability

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Gross margin98.4%-0.2pp
Operating margin-33.3%-11.0pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-67.6%-20.3pp
Debt / equity1.4×+1.1×
Current ratio4.1×-5.6×

Where this comes from

Calculated from Ionis Pharmaceuticals’s reported figures.

Based on trailing twelve months.

The official record: Ionis Pharmaceuticals’s 10-Q, filed April 29, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Ionis Pharmaceuticals's net margin?
Ionis Pharmaceuticals (IONS) reported net margin of -30.9% in Q1 2026.
How has Ionis Pharmaceuticals's net margin changed year-over-year?
Ionis Pharmaceuticals's net margin increased by 51.6% year-over-year, from -63.9% to -30.9%.
What is the long-term trend for Ionis Pharmaceuticals's net margin?
Over 5 years (2020 to 2025), Ionis Pharmaceuticals's net margin has grown at a -7.9% compound annual growth rate (CAGR), from -60.9% to -40.4%.
What does net margin mean?
The share of every sales dollar that becomes bottom-line profit.
How do you interpret net margin?
Higher is better, but net margin mixes operating performance with financing and tax effects and one-off items — read it alongside operating margin to separate the operating story from the rest.
How does net margin compare across companies?
Comparable across peers but sensitive to leverage and tax structure; two operationally identical firms can show different net margins purely from financing.