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Net margin at other companies

Eli Lilly logo
Eli LillyLLY
33.5%+7.6pp
Pfizer logo
PfizerPFE
15.7%
Arrowhead Research logo
Arrowhead ResearchARWR
-48.4%+240pp
BioCryst Pharmaceuticals logo
BioCryst PharmaceuticalsBCRX
-40.9%-50.2pp
ALN
Alnylam PharmaceuticalsALNY
15.3%+10.7pp
Ultragenyx Pharmaceutical logo
Ultragenyx PharmaceuticalRARE
-81.7%-4.9pp

Other financials

Income statement

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Revenue$267.9M-40.7%
Gross profit$265.2M-40.8%
Operating income-$102.3M-173%
Net income-$114.6M-193%
EPS (diluted)-$0.69-199%

Balance sheet

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Cash & equivalents$350.1M+17.7%
Total debt$262.5M-67.0%
Total equity$439.7M-30.4%
Total assets$3.0B+0.3%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$16.1M+30.7%
Free cash flow-$814.6M-399%

Valuation

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Market cap$9.01B+38.9%
Enterprise value$8.92B+27.7%
P/S10.3×+3.4×

Profitability

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Gross margin98.2%-0.7pp
Operating margin-68%-234pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-105.5%+336pp
Debt / equity0.6×-0.7×
Current ratio7.9×+5.0×

Where this comes from

Calculated from Ionis Pharmaceuticals’s reported figures.

Based on trailing twelve months.

The source filing: Ionis Pharmaceuticals’s 10-Q, filed July 29, 2026. Open the filing →

Filed
Jul 29, 2026, 5:05 PM EDT
Fiscal quarter
Q2 FY2026
Calendar quarter
Q2 2026
Accession
0000874015-26-000251

FAQ

What is Ionis Pharmaceuticals's net margin?
Ionis Pharmaceuticals (IONS) reported net margin of -64.7% in Q2 2026.
How has Ionis Pharmaceuticals's net margin changed year-over-year?
Ionis Pharmaceuticals's net margin decreased by 127.6% year-over-year, from -28.4% to -64.7%.
What is the long-term trend for Ionis Pharmaceuticals's net margin?
Over 5 years (2020 to 2025), Ionis Pharmaceuticals's net margin has grown at a -8.2% compound annual growth rate (CAGR), from -61.9% to -40.4%.
What does net margin mean?
Net income as a percentage of revenue (trailing twelve months). The bottom-line profitability measure after all costs, interest, and taxes.

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