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Total Revenue at other companies

Eli Lilly logo
Eli LillyLLY
$19.8B+55.5%
Pfizer logo
PfizerPFE
$14.45B+5.4%
Arrowhead Research logo
Arrowhead ResearchARWR
$73.74M-86.4%
BridgeBio Pharma logo
BridgeBio PharmaBBIO
$194.52M+66.8%
Neurocrine Biosciences logo
Neurocrine BiosciencesNBIX
$814.5M+42.2%
ALN
Alnylam PharmaceuticalsALNY

Segments

By product

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Research And Development Revenue$138.28M+149%
Collaborative Agreement Revenue$120.66M+168%
Commercial$107.81M+41.5%
Royalty$58.32M-9.1%
Spinraza Royalties$43.71M-9.0%
Tryngolza$27.1M+331%

By segment

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Ionis Operations$246.09M+87.0%

Other financials

Income statement

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Gross profit$243.1M+86.8%
Operating income-$117.4M+20.0%
Net income-$92.5M+37.0%
EPS (diluted)-$0.56+39.8%

Balance sheet

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Cash & equivalents$173.4M-34.4%
Total debt$691.7M+334%
Total equity$491.4M+3.3%
Total assets$3.4B+22.6%

Cash flow

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Operating cash flow-$792.8M-426%
CapEx$21.8M+73.0%
Free cash flow-$814.6M-399%

Valuation

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Market cap$12.25B+159%
Enterprise value$12.77B+175%
P/S11.6×+5.0×

Profitability

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Gross margin98.4%-0.2pp
Operating margin-33.3%-11.0pp
Net margin-30.9%-10.5pp
FCF margin-77.4%+35.3pp

Returns & leverage

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Return on equity-67.6%-20.3pp
Debt / equity1.4×+1.1×
Current ratio4.1×-5.6×

Where this comes from

Reported directly by Ionis Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax.

The official record: Ionis Pharmaceuticals’s 10-Q, filed April 29, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Ionis Pharmaceuticals's total revenue?
Ionis Pharmaceuticals (IONS) reported total revenue of $246.09M in Q1 2026.
How has Ionis Pharmaceuticals's total revenue changed year-over-year?
Ionis Pharmaceuticals's total revenue increased by 87.0% year-over-year, from $131.61M to $246.09M.
What is the long-term trend for Ionis Pharmaceuticals's total revenue?
Over 4 years (2021 to 2025), Ionis Pharmaceuticals's total revenue has grown at a 3.9% compound annual growth rate (CAGR), from $810.46M to $943.71M.
What does total revenue mean?
The total income generated from business operations before expenses.
How do you interpret total revenue?
Higher revenue generally signals successful product adoption, market expansion, or effective commercialization strategies.
How does total revenue compare across companies?
The most fundamental metric for cross-company comparison; essential for evaluating market share and growth trajectory.