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Arrowhead Research ARWR Operating margin

Operating margin at other companies

Ionis Pharmaceuticals logo
Ionis PharmaceuticalsIONS
-33.3%-11.0pp
ALN
Alnylam PharmaceuticalsALNY
17.5%+14.4pp
BridgeBio Pharma logo
BridgeBio PharmaBBIO
-90.5%-41.2pp
Madrigal Pharmaceuticals, Inc. logo
Madrigal Pharmaceuticals, Inc.MDGL
-27.7%-12.2pp
Royalty Pharma logo
Royalty PharmaRPRX
65.1%-18.9pp
AbbVie logo
AbbVieABBV
24.4%

Other financials

Income statement

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Revenue$73.7M-86.4%
Operating income-$141.3M-137%
Net income-$132.7M-136%
EPS (diluted)-$0.93-134%

Balance sheet

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Cash & equivalents$188.5M+1.5%
Total debt$107.9M-5.6%
Total equity$614.0M-10.1%
Total assets$2.3B+44.2%

Cash flow

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Operating cash flow$84.4M-81.6%
CapEx$2.6M-51.6%
Free cash flow$81.9M-82.0%

Valuation

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Market cap$11.52B+402%
Enterprise value$11.44B+418%
P/S18.5×+14.3×

Profitability

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Net margin-48.4%+240pp
FCF margin1.8%+0.9pp

Returns & leverage

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Return on equity-46.4%+341pp
Debt / equity0.2×0.0×
Current ratio6.2×+1.1×

Where this comes from

Calculated from Arrowhead Research’s reported figures.

Based on trailing twelve months.

The official record: Arrowhead Research’s 10-Q, filed May 7, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Arrowhead Research's operating margin?
Arrowhead Research (ARWR) reported operating margin of -35.7% in Q1 2026.
How has Arrowhead Research's operating margin changed year-over-year?
Arrowhead Research's operating margin decreased by 64.1% year-over-year, from -21.7% to -35.7%.
What is the long-term trend for Arrowhead Research's operating margin?
Over 5 years (2020 to 2025), Arrowhead Research's operating margin has grown at a -35.5% compound annual growth rate (CAGR), from -105.9% to 11.9%.
What does operating margin mean?
The profit left from core operations for every dollar of sales, before interest and taxes.
How do you interpret operating margin?
Expanding operating margin shows operating leverage — revenue growing faster than the cost base. Compression points to rising overhead, pricing pressure, or investment ahead of revenue.
How does operating margin compare across companies?
Strong cross-company signal within a sector. Capital-light businesses sustain higher operating margins than capital-intensive ones.