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Arrowhead Research

ARWR

Arrowhead Pharmaceuticals is a commercial-stage biotechnology company specializing in medicines that treat intractable diseases by silencing causative genes.

Market cap
$12.05B+455%
Revenue$622.0M+14.1%
Net income-$300.9M-109%
Free cash flow$561.0M+198%
EPS (diluted)-$2.15-54.7%
Trailing twelve months · change vs. prior year

Earnings

Next report

Aug 4, 2026 (In 6 days)
Revenue estimate$44.2M
EPS estimate-$1.28

Financials

Q2 2026

Income statement

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Revenue$73.7M-86.4%
Operating income-$141.3M-137%
Net income-$132.7M-136%
EPS (diluted)-$0.93-134%

Balance sheet

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Cash & equivalents$188.5M+1.5%
Total debt$107.9M-5.6%
Total equity$614.0M-10.1%
Total assets$2.3B+44.2%

Cash flow

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Operating cash flow$84.4M-81.6%
CapEx$2.6M-51.6%
Free cash flow$81.9M-82.0%

Valuation & ratios

Valuation

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Market cap$12.05B+455%
Enterprise value$11.97B+439%
P/S19.4×+15.5×

Profitability

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Operating margin-35.7%+63.6pp
Net margin-48.4%+240pp

Returns & leverage

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Return on equity-46.4%+341pp
Debt / equity0.2×0.0×
Current ratio6.2×+1.1×

Competitors

Profile

Arrowhead Pharmaceuticals is a commercial-stage biotechnology company specializing in medicines that treat intractable diseases by silencing causative genes. The company utilizes a proprietary portfolio of RNA chemistries and delivery mechanisms to trigger RNA interference (RNAi), inducing deep and durable knockdown of target genes across a diverse clinical pipeline.

Competitive position

Arrowhead is a leader in the RNAi space, having transitioned from a R&D-focused entity to a commercial-stage organization with a robust pipeline of 18 clinical candidates.

GeographiesUnited States, Global
Customer segmentsRare disease patients, Healthcare providers, Global pharmaceutical companies
Business modelProduct-based, IP Licensing, Research and Development
SuppliersRaw material suppliers for RNA synthesis, Contract Research Organizations (CROs), Specialized laboratory equipment providers
CustomersSpecialty drug distributors, Health insurance payers, Medical institutions
Listed1995
Employees525.0
CEOChristopher R. Anzalone
FilingsSEC EDGAR

Questions, answered.

What is Arrowhead Research's market cap?
Arrowhead Research (ARWR) has a market capitalization of $12.0B and trades on NASDAQ.
What is Arrowhead Research's revenue and profitability?
Arrowhead Research generated $622.0M in trailing twelve-month revenue with a net loss of $300.9M, representing a net margin of -48.4%, with free cash flow of $561.0M. These figures are based on the Q1 2026 filing.
Who are Arrowhead Research's competitors?
Arrowhead Research's key competitors include Alnylam Pharmaceuticals, Inc., Ionis Pharmaceuticals, Inc., Scienture Holdings, Inc. Common Stock, and others. These companies compete in similar markets and product categories.
Who does Arrowhead Research partner with?
Arrowhead Research's notable partners include Sarepta Therapeutics, Inc., Amgen Inc., Takeda Pharmaceutical Company Limited, and others.
Where is Arrowhead Research headquartered?
Arrowhead Research is headquartered in United States of America and employs approximately 525 people. It has been publicly traded since 1995.