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Alnylam Pharmaceuticals

ALNY

Alnylam Pharmaceuticals is a global commercial-stage biopharmaceutical company that pioneered the development of RNA interference (RNAi) therapeutics.

Market cap
$43.19B-0.2%
Revenue$4.3B+82.6%
Net income$502.3M+318%
Free cash flow$643.3M+931%
EPS (diluted)$3.66+304%
Trailing twelve months · change vs. prior year

Earnings

Next report

Jul 30, 2026 (In 2 weeks)
Revenue estimate$1.3B
EPS estimate$1.61

Financials

Q1 2026

Income statement

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Revenue$1.2B+96.4%
Gross profit$959.7M+83.1%
Operating income$268.6M+1,386%
Net income$206.0M+1,229%
EPS (diluted)$1.51+1,179%

Balance sheet

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Cash & equivalents$1.7B+67.5%
Total debt$263.7M-4.5%
Total equity$1.1B+152%
Total assets$5.1B+21.7%

Cash flow

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Operating cash flow$70.5M+159%
CapEx$21.8M+143%
Free cash flow$48.7M+138%

Valuation & ratios

Valuation

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Market cap$43.19B-0.2%
Enterprise value$41.74B-1.6%
P/E86×
P/S10.1×-7.5×

Profitability

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Gross margin81%-5.3pp
Operating margin17.5%+14.4pp
Net margin11.7%+8.0pp
FCF margin15%+12.7pp

Returns & leverage

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Return on equity66.9%
Debt / equity0.2×-0.4×
Current ratio3.1×+0.1×

Competitors

Profile

Alnylam Pharmaceuticals is a global commercial-stage biopharmaceutical company that pioneered the development of RNA interference (RNAi) therapeutics. The company utilizes small interfering RNA (siRNA) to silence specific messenger RNA (mRNA) molecules, preventing the production of disease-causing proteins. Their platform focuses on genetic medicines for rare and prevalent diseases, leveraging proprietary delivery technologies like GalNAc conjugates and lipid nanoparticles.

Competitive position

Alnylam is the industry leader in RNAi therapeutics, holding the first-mover advantage with multiple approved products and a dominant intellectual property position in siRNA delivery.

GeographiesUnited States, European Union, Global
Customer segmentsHealthcare providers, Patients with rare genetic diseases, Global pharmaceutical companies
Business modelR&D-driven drug development, Product licensing, Direct product sales
SuppliersSpecialized chemical suppliers, Contract manufacturing organizations, Genomic research databases
CustomersWholesale drug distributors, Specialty pharmacies, Health insurance providers, Public health systems
Listed2004
Employees2.1K
CEOYvonne L. Greenstreet
FilingsSEC EDGAR

Questions, answered.

What is Alnylam Pharmaceuticals's market cap?
Alnylam Pharmaceuticals (ALNY) has a market capitalization of $43.2B and trades on NASDAQ.
What is Alnylam Pharmaceuticals's revenue and profitability?
Alnylam Pharmaceuticals generated $4.3B in trailing twelve-month revenue with net income of $502.3M, representing a net margin of 11.7%. Gross margin stands at 81.0%, with free cash flow of $643.3M. These figures are based on the Q1 2026 filing.
Who are Alnylam Pharmaceuticals's competitors?
Alnylam Pharmaceuticals's key competitors include Ionis Pharmaceuticals, Arrowhead Pharmaceuticals, Moderna, and others. These companies compete in similar markets and product categories.
Who does Alnylam Pharmaceuticals partner with?
Alnylam Pharmaceuticals's notable partners include Novartis, Sanofi, Regeneron Pharmaceuticals.
Where is Alnylam Pharmaceuticals headquartered?
Alnylam Pharmaceuticals is headquartered in United States of America and employs approximately 2,100 people. It has been publicly traded since 2004.