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Operating Income at other companies

Ionis Pharmaceuticals logo
Ionis PharmaceuticalsIONS
-$117.42M+20.0%
Arrowhead Research logo
Arrowhead ResearchARWR
-$141.26M-137%
PTC Therapeutics logo
PTC TherapeuticsPTCT
$44.96M-95.4%
Assembly Biosciences logo
Assembly BiosciencesASMB
-$11.37M-14.4%
Arbutus Biopharma Corporation logo
Arbutus Biopharma CorporationABUS
$168.91M+757%
Wave Life Sciences logo
Wave Life SciencesWVE
-$31.3M+37.2%

Other financials

Income statement

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Revenue$1.2B+96.4%
Gross profit$959.7M+83.1%
Net income$206.0M+1,229%
EPS (diluted)$1.51+1,179%

Balance sheet

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Cash & equivalents$1.7B+67.5%
Total debt$263.7M-4.5%
Total equity$1.1B+152%
Total assets$5.1B+21.7%

Cash flow

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Operating cash flow$70.5M+159%
CapEx$21.8M+143%
Free cash flow$48.7M+138%

Valuation

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Market cap$40.19B+0.6%
Enterprise value$38.74B-0.8%
P/E80×
P/S9.4×-6.8×

Profitability

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Gross margin81%-5.3pp
Operating margin17.5%+14.4pp
Net margin11.7%+8.0pp
FCF margin15%+12.7pp

Returns & leverage

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Return on equity66.9%
Debt / equity0.2×-0.4×
Current ratio3.1×+0.1×

Where this comes from

Reported directly by Alnylam Pharmaceuticals in its filing.

Tagged under the XBRL concept us-gaap:OperatingIncomeLoss.

The official record: Alnylam Pharmaceuticals’s 10-Q, filed April 30, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Alnylam Pharmaceuticals's operating income?
Alnylam Pharmaceuticals (ALNY) reported operating income of $268.64M in Q1 2026.
How has Alnylam Pharmaceuticals's operating income changed year-over-year?
Alnylam Pharmaceuticals's operating income increased by 1386.1% year-over-year, from $18.08M to $268.64M.
What is the long-term trend for Alnylam Pharmaceuticals's operating income?
Over 4 years (2021 to 2025), Alnylam Pharmaceuticals's operating income has grown at a -8.3% compound annual growth rate (CAGR), from -$708.65M to $501.58M.
What does operating income mean?
Gross profit minus all operating expenses (SG&A, R&D, D&A). Measures the profit from core business operations before interest, taxes, and non-operating items.