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Operating margin at other companies

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-68%-234pp
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Arrowhead ResearchARWR
-35.7%+63.6pp
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PTC TherapeuticsPTCT
1.6%-38.7pp
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Assembly BiosciencesASMB
-116.8%-26.1pp
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Arbutus Biopharma CorporationABUS
81.7%+42.1pp
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Wave Life SciencesWVE
-75.7%-33.6pp

Other financials

Income statement

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Revenue$1.3B+66.9%
Gross profit$992.7M+57.2%
Operating income$231.4M+1,529%
Net income$164.5M+348%
EPS (diluted)$1.21+337%

Balance sheet

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Cash & equivalents$1.7B+53.2%
Total debt$256.4M-5.2%
Total equity$1.4B+440%
Total assets$5.6B+21.7%

Cash flow

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Operating cash flow$326.7M+113%
CapEx$34.7M+143%
Free cash flow$292.0M+109%

Valuation

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Market cap$27.5B-50.0%
Enterprise value$26.05B-51.9%
P/E37.5×
P/S5.7×-16.6×

Profitability

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Gross margin79.8%-4.1pp
Net margin15.3%+10.7pp
FCF margin16.5%+14.8pp

Returns & leverage

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Return on equity91.4%
Debt / equity0.2×-0.9×
Current ratio3.1×+0.3×

Where this comes from

Calculated from Alnylam Pharmaceuticals’s reported figures.

Based on trailing twelve months.

The source filing: Alnylam Pharmaceuticals’s 10-Q, filed July 30, 2026. Open the filing →

Filed
Jul 30, 2026, 8:11 AM EDT
Fiscal quarter
Q2 FY2026
Calendar quarter
Q2 2026
Accession
0001178670-26-000062

FAQ

What is Alnylam Pharmaceuticals's operating margin?
Alnylam Pharmaceuticals (ALNY) reported operating margin of 20.8% in Q2 2026.
How has Alnylam Pharmaceuticals's operating margin changed year-over-year?
Alnylam Pharmaceuticals's operating margin increased by 384.3% year-over-year, from -7.3% to 20.8%.
What is the long-term trend for Alnylam Pharmaceuticals's operating margin?
Over 5 years (2020 to 2025), Alnylam Pharmaceuticals's operating margin has grown at a -39.6% compound annual growth rate (CAGR), from -168.1% to 13.5%.
What does operating margin mean?
Operating income as a percentage of revenue (trailing twelve months). Captures profitability from core operations after both cost of revenue and operating expenses, but before interest and taxes.

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