What is Wave Life Sciences's return on equity?

Wave Life Sciences (WVE) reported return on equity of -53.7% in Q1 2026.

What is the long-term trend for Wave Life Sciences's return on equity?

Over 2 years (2020 to 2025), Wave Life Sciences's return on equity has grown at a -47.6% compound annual growth rate (CAGR), from -204.6% to -56.2%.

What does return on equity mean?

Trailing-twelve-month net income divided by average shareholders' equity (average of the start and end of the trailing-twelve-month window). Measures the profit generated on each dollar of shareholder capital.

Wave Life Sciences WVE Return on equity

Return on equity at other companies

Eli LillyLLY

107.6%+29.9pp

Sarepta Therapeutics, Inc.SRPT

-23.6%-28.5pp

Ionis PharmaceuticalsIONS

-67.6%-20.3pp

Madrigal Pharmaceuticals, Inc.MDGL

-49.3%-0.8pp

ALN

Alnylam PharmaceuticalsALNY

66.9%—

Beam TherapeuticsBEAM

-47.1%—

Other financials

Income statement

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Revenue$38.2M+317%

Operating income-$31.3M+37.2%

Net income-$26.1M+44.4%

EPS (diluted)-$0.13+55.2%

Balance sheet

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Cash & equivalents$544.6M+124%

Total debt$15.7M-33.4%

Total equity$511.7M+198%

Total assets$583.5M+102%

Cash flow

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Operating cash flow-$59.6M+5.5%

CapEx$438.0K+165%

Free cash flow-$60.0M+5.1%

Valuation

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Market cap$1.14B+13.0%

Enterprise value$615.92M-22.3%

P/S15.1×-12.2×

Profitability

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Operating margin-75.7%-33.6pp

Net margin-66.5%-29.9pp

FCF margin-27.2%-12.6pp

Returns & leverage

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Debt / equity0×-0.1×

Current ratio11.3×+8.3×

Where this comes from

Calculated from Wave Life Sciences’s reported figures.

net income/total stockholders equity=-53.7%

Based on trailing twelve months.

The official record: Wave Life Sciences’s 10-Q, filed April 28, 2026, on SEC EDGAR. View the filing →

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Questions, answered.

What is Wave Life Sciences's return on equity?: Wave Life Sciences (WVE) reported return on equity of -53.7% in Q1 2026.
What is the long-term trend for Wave Life Sciences's return on equity?: Over 2 years (2020 to 2025), Wave Life Sciences's return on equity has grown at a -47.6% compound annual growth rate (CAGR), from -204.6% to -56.2%.
What does return on equity mean?: Trailing-twelve-month net income divided by average shareholders' equity (average of the start and end of the trailing-twelve-month window). Measures the profit generated on each dollar of shareholder capital.